Biobank Based on the i-Share Student Cohort

Completed

• Conditions: Healthy

• Registration Number: NCT02568371
• Lead Sponsor: University Hospital, Bordeaux

Brief Summary

The bio-Share project aims at collecting blood samples in students participating in the i-Share cohort (www.i-share.fr). Investigators aim at setting up a platform that will enable investigators in the future to study biological determinants of conditions that affect young adults and to test certain hypotheses on the pathophysiology and mechanisms underlying diseases occurring both at a young age and later in life (as early exposures may also impact late onset diseases)

Detailed Description

The i-Share cohort was set up to study various important aspects of students' health and to better understand early mechanisms contributing to the occurrence of common diseases representing an important public health burden. The i-Share cohort is funded by an "investment for the future grant" from the French National Research Agency (ANR-10-COHO-05-01) with the aim to recruit 30000 students at the University of Bordeaux, and a few additional partner universities in France and abroad (www.i-share.fr).

The bio-Share study is a biological repository embedded within the i-Share study, aiming at collecting blood samples (for genetic analyses as well as measurement of other biomarkers) from a subset of 2000 i-Share participants volunteering for this ancillary project.

The goal is to set up a platform that will enable investigators in the future to study biological determinants of conditions that affect young adults and to test certain hypotheses on the pathophysiology and mechanisms underlying diseases occurring both at a young age and later in life (as early exposures may also impact late onset diseases).

The biobank will comprise the following biological materials: plasma, serum, whole blood, red blood cells, DNA, RNA. Levels of fasting glucose and lipid levels (total cholesterol, HDL-cholesterol, LDL-cholesterol, triglycerides) will be returned to participants.

Study Timeline

• Study First Submitted: 2015-10-02
• Study First Submitted QC: 2015-10-02
• Study First Posted: 2015-10-05
• Study Start: 2015-10-06
• Primary Completion: 2017-11-30
• Study Completion: 2017-11-30
• Status Verified: 2019-03
• Last Update Submitted: 2019-03-14
• Last Update Posted: 2019-03-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 1997

Inclusion Criteria

• Be an i-Share participant in Bordeaux
• Being aged 18 years or more
• Being affiliated or beneficiary of a social security
• Having filled out the first online i-Share questionnaire
• Having signed a written informed consent

Exclusion Criteria

• Pregnant or breastfeeding women,
• Persons who cannot personally give their consent and adults under guardianship.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The total volume of the aliquots for each of the stored biological samples	Day 1
The acquisition date of blood samples	Day 1
The number of the aliquots for each of the stored biological samples	Day 1

Secondary Outcome Measures

Name	Time	Method
Glucose (fasting)	Day 1
Total cholesterol (fasting)	Day 1
Low-density lipoprotein-cholesterol (fasting)	Day 1
High-density lipoprotein cholesterol (fasting)	Day 1
Triglycerides (fasting)	Day 1

Trial Locations

Locations (1)

Centre Hospitalier Universitaire de Bordeaux - PELLEGRIN; 🇫🇷 Bordeaux, Aquitaine, France