The effect of high-polyphenol olive oil in cardiovascular risk markers in healthy adults

Not Applicable

Completed

• Conditions: Cardiovascular disease; Mild cognitive decline; Cardiovascular - Coronary heart disease; Neurological - Studies of the normal brain and nervous system

• Registration Number: ACTRN12618000706279
• Lead Sponsor: a Trobe University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-04-30
• Study Completion: 2019-10-05
• Last Update Posted: 10 February 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Aged 18-75 years

Exclusion Criteria

The exclusion criteria of Post and peri-menopausal women has been removed. More specifically the updated list of the key exclusion criteria is as follows:
Non-English-speaking persons
• Pregnant or lactating women
• History of adverse reactions to olive oil (
• Currently prescribed warfarin, anti-coagulant therapy, statin medications, all oral hypoglycaemic agents, insulin, cyclosporine, tacrolimus, immunosuppressant agents, antihypertensive agents, and nonsteroidal anti-inflammatory drugs (hypothesised interactions), hormone replacement therapy
• A habitual diet with greater than or equal to 1 tablespoon of olive oil per day;
• Current smoker;
• Use of antioxidant supplements or medications with antioxidant properties,
• Diagnosed with any of the following conditions: hyperlipidaemia; diabetes mellitus; hypertension; inflammatory conditions (e.g. rheumatoid arthritis), intestinal disease (e.g. inflammatory bowel disease); irritable bowel syndrome, food intolerances, blood coagulation disorders, or any other physiological condition or disease that could impair adherence.
-Unstable body weight within =/>5kg weight fluctuations in the prior 3 months
-Special diet for medical reasons (i.e gluten free for coeliac disease)

Exclusion criteria for cognition component only.
-Currently prescribed antidepressant medication

Study & Design

• Study Type: Interventional
• Study Design: Not specified