Crossover study of diets enriched with virgin olive oil, walnuts or almonds. Effects on lipids and other cardiovascular risk markers

Completed

• Conditions: utrition; Nutritional, Metabolic, Endocrine

• Registration Number: ISRCTN68210440
• Lead Sponsor: International Nut and Dried Fruit Foundation (Spain)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2010-12-14
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

1. Asymptomatic men and women with moderate hypercholesterolemia, age 25 to 75 years (after menopause in women)
2. Serum LDL cholesterol more than 3.36 mmol/L
3. Triglycerides less than 2.82 mmol/L
4. Absence of chronic illnesses or secondary hypercholesterolemia
5. No known allergy to nuts
6. Participants can be under stable lipid-lowering drug treatment (statins or fibrates, statins at doses of no more than simvastatin 40 mg/day or equivalent)
7. Written informed consent

Exclusion Criteria

1. Subjects on a weight-losing diet
2. Familial hypercholesterolemia
3. Established type 2 diabetes
4. Fatty food intolerance
5. Consumption of products that can influence cholesterol metabolism (other than statins and fibrates), such as resins, ezetimibe, psyllium, fish oil concentrates, soy lecithin, or phytoestrogens

Study & Design

• Study Type: Interventional
• Study Design: Not specified