The effect of consuming olive oil in patients with depressio
- Conditions
- Depression.Depressive episode
- Registration Number
- IRCT2016041820140N3
- Lead Sponsor
- Vice Chancellor for Research of Shiraz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 73
Main inclusion criteria: Suffering from major depression based on criteria of Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition; aged 18 to 65 years old; routine consumption of sunflower oil; without allergy to olive or sunflower or their products; without fat malabsorption; a score of less than or equal to 7 in 14-item questionnaire of Mediterranean diet adherence and ability and willingness to participate in the study. Main exclusion criteria: Use of lipid lowering medications; use of corticosteroid medications; suffering from a concurrent serious mental disorder such as schizophrenia; suffering from severe or unstable medical conditions; alcohol or drug dependence; pregnancy; lactation; serious risk of homicide or suicide; the need for hospitalization; change in medications or treatments used for depression; change in diet or physical activity; consumption of less than 70% of the recommended oil and loss of any of the inclusion criteria.
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Anthropometric indices (body mass index, waist-to-height ratio). Timepoint: The beginning, middle and end of the study. Method of measurement: Using the weighing scale with the accuracy of 0.1 kg and measuring tapes with the accuracy of 0.1 cm.;Blood pressure. Timepoint: The beginning, middle and end of the study. Method of measurement: In millimeters of mercury using the mercury sphygmomanometer.;Serum high-sensitivity C-reactive protein. Timepoint: The beginning and end of the study. Method of measurement: In milligrams per liter using the assay kit.;Serum malondialdehyde. Timepoint: The beginning and end of the study. Method of measurement: In micromolars using the assay kit.
- Secondary Outcome Measures
Name Time Method