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临床试验/NCT07098871
NCT07098871已完成不适用

The Role of Preoperative Rectus Abdominis and Diaphragm Muscle Thickness in Predicting Postoperative Complications in Patients Undergoing Surgery for Gastrointestinal Malignancies: A Prospective Observational Study

Ankara Oncology Research and Training Hospital1 个研究点 分布在 1 个国家目标入组 129 人开始时间: 2025年9月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
129
试验地点
1
主要终点
Correlation between rectus muscle thickness and clavien-dindo grade of postoperative complications

研究概览

简要总结

The aim of this observational study is to investigate the relationship between preoperative rectus abdominis and diaphragm muscle thickness and postoperative complication rates in patients undergoing surgery for gastrointestinal system malignancies.

The main research question is whether rectus abdominis and diaphragm muscle thickness can be used to predict postoperative complications in these patients, and whether there are specific cut-off values for these muscle thicknesses.

Participants will be selected from operable gastrointestinal malignancy cases, and preoperative measurements of rectus abdominis and diaphragm muscle thickness will be performed using ultrasonography.

详细描述

Background and Aim:

Gastrointestinal system (GIS) malignancies are commonly encountered and carry a significant risk of serious complications following surgery. Therefore, several studies in the literature have focused on identifying parameters that can predict the risk of postoperative complications in patients undergoing surgery for GIS malignancies. Some publications have suggested that preoperative nutritional indices may help predict the development of complications, evaluating specific parameters through biochemical tests or radiological assessments of muscle and fat mass.

In our study, we aim to investigate the relationship between preoperative rectus abdominis and diaphragm muscle thickness-measured via ultrasonography during routine fascial block procedures-and the rate of complications occurring within the first 30 days postoperatively in patients undergoing surgery for GIS malignancies.

Methodology:

Patients whose rectus abdominis and diaphragm muscle thickness were measured during routine preoperative fascial block ultrasonography will be included in the study. No additional intervention or procedure is planned; patients will be evaluated as part of standard clinical practice, and their postoperative outcomes will be recorded observationally. No additional tests requiring reimbursement from the national health insurance system will be performed as part of the study.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者
否

入选标准

  • •Age over 18 years
  • •Patients scheduled for laparoscopic or open surgery due to GIS malignancy between 01.05.2025 and 01.11.2025
  • •Postoperative follow-up at our center for a minimum of 30 days

排除标准

  • •Age under 18 years
  • •Patients not undergoing surgery
  • •Patients undergoing surgery for indications other than GIS malignancy
  • •Patients with follow-up data shorter than 30 days

研究组 & 干预措施

Surgery

Patients undergone surgery for gastrointestinal system malignancies

干预措施: Ultrasonography (Rectus and diaphragma muscle thickness measurement) (Diagnostic Test)

结局指标

主要结局

Correlation between rectus muscle thickness and clavien-dindo grade of postoperative complications

时间窗: From enrollment to 30th postoperative day.

Correlation between rectus muscle thickness and clavien-dindo grade of postoperative complications

Correlation between diaphragma muscle thickness and clavien-dindo grade of postoperative complications

时间窗: From enrollment to 30th postoperative day.

Correlation between diaphragma muscle thickness and clavien-dindo grade of postoperative complications

Correlation between rectus muscle thickness and clavien-dindo grade of postoperative complications

时间窗: From enrollment to 30th postoperative day.

Correlation between rectus muscle thickness and clavien-dindo grade of postoperative complications

Correlation between diaphragma muscle thickness and clavien-dindo grade of postoperative complications

时间窗: From enrollment to 30th postoperative day.

Correlation between diaphragma muscle thickness and clavien-dindo grade of postoperative complications

次要结局

未报告次要终点

研究者

发起方
Ankara Oncology Research and Training Hospital
申办方类型
Network
责任方
Principal Investigator
主要研究者

Burak Dincer

Principal Investigator

Ankara Oncology Research and Training Hospital

研究点 (1)

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