The Relationship Between Hypoalbuminemia and Development of Acute Kidney Failure (AKI) According to KDIGO Criteria

• Conditions: Acute Kidney Failure; Hypoalbuminemia
• Interventions: Other: hypoalbuminemia

• Registration Number: NCT03675906
• Lead Sponsor: Erzincan University

Brief Summary

This study was designed to determine the association between preoperative and postoperative hypoalbuminemia and AKI in older age hip fracture surgeons, to determine which period of hypoalbuminemia contributes more to AKI development, the incidence of AKI according to anesthesia type, the presence of other factors affecting AKI development, the duration of hospitalization and cost- to be investigated.

Detailed Description

Not available

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Status Verified: 2018-09
• Study Start: 2018-09-12
• Study First Submitted: 2018-09-12
• Study First Submitted QC: 2018-09-17
• Last Update Submitted: 2018-09-17
• Study First Posted: 2018-09-18
• Last Update Posted: 2018-09-18
• Primary Completion: 2018-12-15
• Study Completion: 2018-12-30

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 160

Inclusion Criteria

• patients with femur fracture surgery
• 65 years and over
• Patients with ASA I - IV physical condition
• patients with spinal anesthesia or peripheral nerve block

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Exclusion Criteria

• Patients undergoing emergency surgery
• patients with preoperative serum creatinine (sCr) level> 1.5 mg / dl
• patients with low serum albumin levels in both preoperative and postoperative periods
• patients receiving preoperative ventilator care
• patients with spinal anesthesia or peripheral nerve block contraindications (coagulopathies, local infection at the puncture site, spot infection) or nonsteroidal antiinflammatory drug (NSAID)

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
preoperative albumin levels <3.8	hypoalbuminemia	-
postoperative Day 2 albumin level >2.9	hypoalbuminemia	-
preoperative albumin level >3.8	hypoalbuminemia	-
postoperative Day 2 albumin level <2.9	hypoalbuminemia	-

Primary Outcome Measures

Name	Time	Method
hypoalbuminemia and AKI - incidence of AKI	3 months	hypoalbuminemia and incidence of AKI according to KDIGO criterias

Secondary Outcome Measures

Name	Time	Method
anesthesia type - incidence of AKI	3 months	incidence of AKI according to anesthesia type

Trial Locations

Locations (1)

Erzincan University; 🇹🇷 Erzincan, Turkey