KCT0001500
Completed
未知
Population pharmacokinetics and pharmacodynamics of ramosetron
ConditionsNot Applicable
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Not Applicable
- Sponsor
- Asan Medical Center
- Enrollment
- 51
- Status
- Completed
- Last Updated
- 7 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\) American Society of Anesthesiologists (ASA) physical status 1 or 2
- •2\) Age over 20
- •3\) Patients scheduled for elective surgery under general anesthesia
- •4\) Patients who volunteered
- •5\) Patients who have more than 2 factors of Apfel's PONV risk factor
- •6\) Patients scheduled for elective stomach, colorectal surgery under laparotomy or laparoscopy
Exclusion Criteria
- •1\) Age less than 20
- •2\) History of anaphylactic response to fentanyl, ketorolac, or ramosetron
- •3\) Patients who received antiemetics, steroids, antihistamines, or antipsychotic drugs that can affect PONV, within 24 hours before surgery
- •4\) ASA physical status over 3
- •5\) Patients planned for maintaning nasogastric tube postoperatively
- •6\) Patients with hemoglobin level less than 10\.0 g/dl preoperatively
- •7\) Patients who participated in clinical trial on other drugs, within 30 days before screening
- •8\) Patients who donated blood over 450 ml, within 30 days before screening
- •9\) Active hepatitis (HIV postitive, history of HBV, HCV, and positive on serologic tests)
- •10\) Binge drinking\* or clinically significant alcoholics\*\*
Outcomes
Primary Outcomes
Not specified
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