Comparison of two methods to treat obesity hypoventilation syndrome: Noninvasive ventilation (NIV) and continuous positive airway pressure (CPAP)

Not Applicable

Completed

• Conditions: Obesity hypoventilation syndrome; Respiratory

• Registration Number: ISRCTN13981084
• Lead Sponsor: Alain Palot

Brief Summary

2017 results in https://pubmed.ncbi.nlm.nih.gov/28288605/ (added 26/11/2020)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-02-27
• Study Completion: 2017-03-31
• Last Update Posted: 7 December 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 22

Inclusion Criteria

1. 18 years old or older
2. Suffering from obesity hypoventilation syndrome (OHS) defined as an association of obesity (BMI = 30 kg/m²) and daytime hypercapnia (paCO2 > 45 mm Hg))
3. Patients who had been undergoing noninvasive ventilation (NIV) for more than 2 months
4. Clinically stable for at least 4 weeks before enrollment in the study (no hospitalization or emergency admission)

Exclusion Criteria

1. Hypercapnia secondary to other causes (obstructive pulmonary diseases (FEV1/FVC < 70), interstitial lung diseases, neuromuscular or chest wall diseases, severe hypothyroidism or congenital central hypoventilation syndrome)
2. Patients unable to give informed consent to data collection and analysis

Study & Design

• Study Type: Observational
• Study Design: Not specified