NCT05874674招募中不适用
The Safety of Nafamostat Mesylate for Patients With High Risk Bleeding Diathesis Undergoing Hemodialysis: A Pilot Study
Wonju Severance Christian Hospital1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2023年12月1日最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Number of patients with severe bleeding
研究概览
简要总结
Comparison nafamostat and low molecular weight heparin among dialysis patients
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 18 Years 至 99 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •platelet below 10k PTT above 60 second INR above 20 patient with bleeding (epistaxis, orbital bleeding, hematuria) recent brain hemorrhage (within 6 months) receiving anticoagulant therapy (coumadin or NOAC) dual antiplatelet agent users received major surgery within one month
排除标准
- •cancer liver cirrhosis pregnancy drug allergy current bleeding on major organ (brain, gastrointestinal)
研究组 & 干预措施
nafamostat
Active Comparator
Patients received dialysis through nafamostat
干预措施: Nafamostat Mesylate (Drug)
结局指标
主要结局
Number of patients with severe bleeding
时间窗: 6 month
Brain hemorrhage (on brain CT), gastrointestinal bleeding (on EGD)
次要结局
- Number of patients with dialysis circuit clot(6 month)
研究者
研究点 (1)
Loading locations...
相似试验
已完成
4 期
The Effect of Nafamostat Mesilate in Prolonging Filter Patency With Patients on Continuous Renal Replacement TherapyAcute Kidney InjuryNCT01761994Yonsei University66
招募中
Unknown
Effect of dialysis fluid temperature in haemodialysisIRCT20240511061739N1Pak Emirates Military Hospital50
招募中
不适用
Effect of Low Versus High Dialysate Sodium Concentration During Hemodialysis on Dialysis Recovery TimeComplications DialysisNCT05418647Alexandria University40
招募中
3 期
Comparing the efficacy of heparin lock and Dialysate flushing for preventing peritoneal dialysis catheter blockagethrombosis in peritoneal dialysis catheter at two and four weeks after insertion.Heparin locked, PD catheter, thrombosis, fibrin clotted,TCTR20221111002Faculty of Medicine, Siriraj Hospital, Mahidol University120
已完成
不适用
Effect of Different dialysates on serum potassiumhyperkalemia in hemodialysis patients.Chronic kidney disease, stage 5N18.5IRCT20220703055361N1Esfahan University of Medical Sciences160