Inferior Vena cavaCollapsibility Index in Patients With Acute Kidney Injury

Completed

• Conditions: Acute Kidney Injury

• Registration Number: NCT02165072
• Lead Sponsor: Texas Tech University Health Sciences Center

Brief Summary

This is an observational study that will examine the possibility of determining the type of Acute Kidney Injury (AKI) using bedside ultrasound machines.

Detailed Description

The investigators hypothesize that different types of AKI (pre-renal, renal, and post-renal) are associated with different inferior vena cava diameters and collapsibility index. The investigators will include subjects ages 18-89 years with AKI (creatinine of 2mg/100ml or higher for less than 24 hours from baseline creatinine ≤1.2 or with unknown baseline creatinine). Standard of care treatment will not be different for patients taking part in this study. Participants will have bedside ultrasounds on days 0, 1, and 3, and baseline and follow-up data will be collected from medical records.

Study Timeline

• Study Start: 2014-02
• Study First Submitted: 2014-06-13
• Study First Submitted QC: 2014-06-16
• Study First Posted: 2014-06-17
• Primary Completion: 2015-10
• Study Completion: 2015-10
• Results First Submitted: 2015-11-02
• Status Verified: 2016-06
• Results First Submitted QC: 2016-06-21
• Last Update Submitted: 2016-06-21
• Results First Posted: 2016-06-23
• Last Update Posted: 2016-06-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

1. Creatinine of 1.7 mg/100ml or higher for less than 24 hours from baseline creatinine ≤1.2 or with unknown baseline creatinine
2. Age range: 18-89 years
3. Age range ≥ 18

Exclusion Criteria

1. Only chronic renal disease will exclude a patient from our study regardless of past medical history and medications they are taking. (For the purposes of this study, any patient with creatinine higher than 1.2 mg /100ml for more than 24 hours will be identified as having chronic renal disease.)

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Maximum and Minimum Diameters of the Inferior Vena Cava in Patients With Acute Kidney Injury	Day 1 of ICU admission	The investigators will measure the maximum and minimum diameters of the inferior vena cava with patients with acute kidney injury.
Percent Collapse of the Inferior Vena Cava in Patients With Acute Kidney Injury	Day 1 of ICU admission	The investigators will measure the maximum and minimum diameters of the inferior vena cava with patients with acute kidney injury and calculate the percent change between the maximum and minimum diameters.

Trial Locations

Locations (1)

Texas Tech Univrsity Health Science Center; 🇺🇸 Lubbock, Texas, United States