Effects of lanthanum carbonate on arterial stiffness in patients with CKD 3-5 not on dialysis
Not Applicable
- Conditions
- non-dialysis chronic kidney disease
- Registration Number
- JPRN-UMIN000016605
- Lead Sponsor
- Kurume University School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 120
Inclusion Criteria
Not provided
Exclusion Criteria
1) <20years old 2) Treatment with lanthanum carbonate within the past two months 3) Contraindications to lanthanum carbonate 4) Inflammatory disease 5) Malignancy of any type 6) History of renal transplantation 7) Pregnant or breast-feeding women 8) Ineligible patients for this study according to the investigator's judgment
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change from baseline and compare between 2 groups, as follows : Pulse wave velocity, Left ventricular mass and oxidative stress makers (nitrotyrosine, AGE, RAGE, Urinary 8-OHdG, Skin accumulation of AGE)
- Secondary Outcome Measures
Name Time Method Change from baseline and compare between 2 groups, as follows: Phosphate, Calcium, FGF-23, soluble alfa-Klotho , iPTH, eGFR, Cr,1/Cr, OC, CRP