Measurement of Expiratory Gas Temperature in Intubated Patients to Estimate Expiratory Absolute Humidity
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 70
- 试验地点
- 1
- 主要终点
- Expiratory gas temperature
研究概览
简要总结
Adequate humidification is essential for intubated patients because dry medical gases can cause thick secretions and dangerous endotracheal tube blockages. A clear correlation exists between exhaled and inhaled humidity delivered by heat and moisture exchanger. The objective of this study is to measure the temperature of exhaled gases in intubated patients in order to accurately calculate the absolute humidity during the expiratory phase. These data will allow for a more accurate reproduction of real clinical conditions during bench testing and will improve the assessment of heat and moisture exchanger performance device evaluation.
详细描述
Previous clinical studies suggest that real expiratory humidity in intubated patients is close to 35 mg H₂O/L, with expiratory temperatures around 32-33 °C or slightly lower. However, data are limited, heterogeneous, and often derived from anesthetized patients. Therefore, accurate measurement of expiratory temperature in intensive care patients under normothermia and across varying body temperatures is necessary to define realistic simulation standards and ensure reliable heat and moisture exchanger performance evaluation on a bench. A relationship between expiratory gases temperature and expiratory humidity exist.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adults (≥18 years)
- •Intubated and mechanically ventilated in the intensive care unite
- •Using passive humidification (Heat and Moisture exchanger)
排除标准
- •PEEP set < 12 cmH₂O
- •Inhaled nitric oxide therapy
- •Tracheostomy
研究组 & 干预措施
Normothermic patient
Normothermic patient under mechanical ventilation with passive humification (heat and moisture exchanger) with body temperature between 36.0 and 38.0 Celsius degrees
干预措施: Expiratory gases temperature (Other)
Hypothermic patient
Hypothermic patient under mechanical ventilation with passive humification (heat and moisture exchanger) with body temperature < 36.0 Celsius degrees
干预措施: Expiratory gases temperature (Other)
Hyperthermic patient
Hyperthermic patient under mechanical ventilation with passive humification (heat and moisture exchanger) with body temperature > 38.0 Celsius degrees
干预措施: Expiratory gases temperature (Other)
结局指标
主要结局
Expiratory gas temperature
时间窗: H0, up to 60 minutes after inclusion
Measure expiratory gas temperature immediately before the passive humidifier
Relationship between body temperature and expiratory temperature.
时间窗: H0, up to 60 minutes after inclusion
Evaluate the relationship between body temperature and expiratory temperature
次要结局
- Estimate expiratory absolute humidity based on measured temperature(H0, up to 60 minutes after inclusion)
研究者
François Lellouche
Principal Investigator
Laval University