Comparison of ultrasound based assessment of renal blood flow with laboratory based blood tests for early prediction of kidney dysfunction after cardiac surgery using heart-lung machine
Not Applicable
Recruiting
- Conditions
- Health Condition 1: I00-I99- Diseases of the circulatory system
- Registration Number
- CTRI/2023/06/053735
- Lead Sponsor
- Department of Anaesthesiology Critical Care AFMC
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1) Patients undergoing cardiac surgery on cardiopulmonary bypass
2) ASAI to IV
Exclusion Criteria
1)Dialysis dependent kidney disease
2)Post renal transplant cases
3)Death within 48hrs post op
4)Renal artery stenosis
with psychiatric illness/ alcohol abuse
5)Patients without satisfactory pulse wave doppler of renal interlobar or arcuate artery
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the efficacy of prediction of AKI with RRI by ulatrsonography and NL Ratio from blood tests in patients undergoing cardiac surgeries on CPBTimepoint: Assessment by renal resistive index by ultrasonography and calculation of NL ratio from blood tests will done at four time points - before surgery (preop), on postop evening, postop day 1 and postop day 3.
- Secondary Outcome Measures
Name Time Method To study the association of abnormal RRI and NLR with development of AKI in patients undergoing cardiac surgeries on CPBTimepoint: May 2023 to August 2024
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms link renal resistive index and neutrophil/lymphocyte ratio to acute kidney injury after cardiopulmonary bypass?
How does ultrasound-based renal resistive index compare to serum creatinine in predicting post-cardiac surgery acute kidney injury?
Which biomarkers, including cystatin C and NGAL, correlate with renal resistive index for early AKI detection in cardiac surgery patients?
What adverse events are associated with cardiopulmonary bypass-induced acute kidney injury and how can RRI/NLR monitoring mitigate them?
Are there non-invasive imaging techniques or biomarkers that outperform RRI and NLR in predicting AKI after cardiac surgery?