Impact of epileptic activity on cognitive function in epileptic encephalopathies
- Conditions
- G40Epilepsy
- Registration Number
- DRKS00032991
- Lead Sponsor
- niversitätsklinikum Schleswig-Holstein
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 75
a)Age 6 – 12 years
b)Both genders
c)30-45 children with BECTS: (1) standard wake EEG showing a normal background and at least one focus of spike-waves in the centro-temporal region (maximum electronega-tivity at electrodes C3, C4, T3 or T4, according to the international 10–20 electrode placement system; (2) normal neurological examination; (3) absence of mental retar-dation (Perceptual Reasoning Index > 80); (4) Normal structural MRI (5); if epileptic sei-zures had occurred, semiology of seizures suggestive of BECTS; (6) patients are not un-der antiepileptic drug treatment.
d)30 children with CSWS (more the 85% of EEG is involved in spiking activity according to the spike index)
e)30 children with partial epilepsy associated with focal lesional epilepsy
f)IQ > 65
a)Mental retardation (IQ < 65)
b)Cerebral palsy
c)History of convulsive status epilepticus
d)A clinical diagnosis of autism in children with BECTS
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.