DRKS00032991
Completed
Not Applicable
Impact of epileptic activity on cognitive function in epileptic encephalopathies - DESIRE
niversitätsklinikum Schleswig-Holstein0 sites75 target enrollmentNovember 24, 2023
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- G40
- Sponsor
- niversitätsklinikum Schleswig-Holstein
- Enrollment
- 75
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •a)Age 6 – 12 years
- •b)Both genders
- •c)30\-45 children with BECTS: (1\) standard wake EEG showing a normal background and at least one focus of spike\-waves in the centro\-temporal region (maximum electronega\-tivity at electrodes C3, C4, T3 or T4, according to the international 10–20 electrode placement system; (2\) normal neurological examination; (3\) absence of mental retar\-dation (Perceptual Reasoning Index \> 80\); (4\) Normal structural MRI (5\); if epileptic sei\-zures had occurred, semiology of seizures suggestive of BECTS; (6\) patients are not un\-der antiepileptic drug treatment.
- •d)30 children with CSWS (more the 85% of EEG is involved in spiking activity according to the spike index)
- •e)30 children with partial epilepsy associated with focal lesional epilepsy
Exclusion Criteria
- •a)Mental retardation (IQ \< 65\)
- •b)Cerebral palsy
- •c)History of convulsive status epilepticus
- •d)A clinical diagnosis of autism in children with BECTS
Outcomes
Primary Outcomes
Not specified
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