Comparison of cognitive impairment and seizure characteristics in manic patients receiving electroconvulsive therapy with or without concurrent treatment with sodium valproate.
Not Applicable
- Conditions
- Bipolar disorder,Manic episode.Manic episode
- Registration Number
- IRCT201101011743N4
- Lead Sponsor
- Hamedan univercity of medical science
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
1. Manic episode based on DSM IV-TR
2. Age between 18 and 60 years
3. Elementary school education (at least)
4. ECT administer by attending physician
Exclusion criteria:
1.Concurrent anticonvulsant therapy (except sodium valproate)
2. Severe cognitive impairment (MMSE = 19) befor the first session of ECT
3.Uncontrolled physical condition
4.Pregnant and nursing women
5. History of epilepsy
6. LFT > 3 fold the normal range
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Seizure threshold. Timepoint: all session of ECT. Method of measurement: observation.;Duration of seizure. Timepoint: all session of ECT. Method of measurement: EEG.;Cognetive side effect. Timepoint: Befor the 1st ECTsession and after 3rd and 6th session. Method of measurement: MMSE.
- Secondary Outcome Measures
Name Time Method