An Observational Study Based on Endometrial Cancer Risk Screening Model

• Conditions: Endometrial Neoplasms

• Registration Number: NCT05634798
• Lead Sponsor: Peking Union Medical College Hospital

Brief Summary

The goal of this observational study is to test the efficiency of our endometrial cancer risk screening calculator, and improve the endometrial cancer risk screening model to form a stable and reliable non-invasive auxiliary diagnostic tool with high sensitivity and specificity in healthy women.The main question it aims to answer is:

·the efficiency of our endometrial cancer risk screening calculator Participants will be collected demographic information, as well as ultrasound, blood routine test and other test results, which will be entered into the endometrial cancer risk screening calculator to obtain high-risk or low-risk prediction results.

Detailed Description

Not available

Study Timeline

• Status Verified: 2022-05
• Study First Submitted: 2022-11-22
• Study First Submitted QC: 2022-11-22
• Last Update Submitted: 2022-11-22
• Study Start: 2022-12-01
• Study First Posted: 2022-12-02
• Last Update Posted: 2022-12-02
• Primary Completion: 2023-12-01
• Study Completion: 2023-12-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 2000

Inclusion Criteria

1. Age: 18-70;
2. The annual update of questionnaire information required by the calculator can be completed, and the gynecological examination, gynecological B-ultrasound and blood test can be evaluated once a year, and the follow-up can be at least 1 year; The patient or family members can understand the research scheme and are willing to participate in the study, and provide e-book informed consent.

Exclusion Criteria

1. Endometrial cancer or precancerous lesions have been diagnosed;
2. Previous or current malignant tumor, currently receiving radiotherapy and chemotherapy, endocrine, targeted and immunotherapy;
3. History of endometrial resection or total hysterectomy;
4. Pregnant or lactating women;
5. The patient or family member could not understand the conditions and objectives of this study.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
No endometrial cancer or precancerous lesions	1 year	The study object did not show B-ultrasound and clinical symptoms which indicate endometrial cancer or precancerous lesions.
Obtained endometrial pathological specimens due to any factors	1 year	The study object was obtained endometrial pathological specimen within one year due to any factor.

Trial Locations

Locations (1)

Peking Union Medical College Hospital; 🇨🇳 Beijing, Beijing, China