A Prospective, Multicenter Registry With Targeted Temperature Management After Out-of-hospital Cardiac Arrest in Korea
- Conditions
- Out-of-Hospital Cardiac Arrest
- Registration Number
- NCT02827422
- Lead Sponsor
- Kyu Nam Park
- Brief Summary
Therapeutic hypothermia after out-of-hospital cardiac arrest is considered as a standard care. However, optimal candidates, optimal dose, duration, timing of initiation and rate of rewarming is still unknown. The objective of this project is to improve the outcomes for patients after resuscitation from out-of-hospital cardiac arrest treated with therapeutic hypothermia established from the analysis of multicenter registry data.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 1800
Inclusion Criteria
- age of older than 18 years
- out-of-hospital cardiac arrest
- comatose mentality after return of spontaneous circulation (ROSC)
- treated with therapeutic hypothermia, regardless of target temperature
Exclusion Criteria
- suspected or confirmed to cerebrovascular accident
- poor pre-arrest neurologic status (CPC>3)
- patients who are terminally ill or for whom intensive care dose not seem to be appropriate
- Do not attempt resuscitation (DNAR) order
- patients with tympanic membrane temperature below 30 degree celsius on admission
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method survival 6 months after cardiac arrest Neurologic Outcome after 6 months modified Rankin Scale (mRS) mRS 0,1,2, 3 : Good Outcome mRS 4,5,6 : Poor Outcome
- Secondary Outcome Measures
Name Time Method survival duration of hospitalization, limit 180 days neurological outcome 1 month after cardiac arrest modified Rankin Scale (mRS) mRS 0,1,2, 3 : Good Outcome mRS 4,5,6 : Poor Outcome
Survival 1 month after cardiac arrest
Trial Locations
- Locations (1)
Seoul St. Mary's Hospital, The Catholic University of Korea
🇰🇷Seoul, Korea, Republic of
Seoul St. Mary's Hospital, The Catholic University of Korea🇰🇷Seoul, Korea, Republic ofKyu Nam Park, MD, PhDContact82-2-2258-6301emsky@catholic.ac.krJi Hoon Kim, MD, PhDPrincipal InvestigatorWon Jung Jeong, MDPrincipal InvestigatorSeung Pill Choi, MD, PhDPrincipal InvestigatorMi Jin Lee, MD, PhDPrincipal InvestigatorJong-Seok Lee, MD, PhDPrincipal InvestigatorSu Jin Kim, MD, PhDPrincipal InvestigatorTae Chang Jang, MD, PhDPrincipal InvestigatorInbyung Kim, MDPrincipal InvestigatorYong Hwan Kim, MDPrincipal InvestigatorWon Young Kim, MD, PhDPrincipal InvestigatorJonghwan Jonghwan, MDPrincipal InvestigatorJi Hwan Lee, MDPrincipal InvestigatorGiwoon Kim, MDPrincipal InvestigatorWook-jin Choi, MD, PhDPrincipal InvestigatorJoo Suk Oh, MD PhDPrincipal InvestigatorChul Han, MD, PhDPrincipal InvestigatorByung Kook Lee, MD, PhDPrincipal InvestigatorTaeoh Jeong, MD, PhDPrincipal InvestigatorDong Hoon Lee, MD, PhDPrincipal InvestigatorJin Hong Min, MDPrincipal InvestigatorGyu Chong Cho, MD, PhDPrincipal InvestigatorYoung Hwan Lee, MDPrincipal InvestigatorIn Soo Cho, MDPrincipal InvestigatorJe Sung You, MD, PhDPrincipal InvestigatorChangsun Kim, MD. PhDPrincipal InvestigatorKyoung-Chul Cha, MDPrincipal InvestigatorSoo Hyung Cho, MD. PhDPrincipal Investigator