Efficacy between intravenous magnesium sulphate and dexmedetomidine as premedication in attenuation hemodynamic stress response during laparoscopic cholecystectomy
Phase 2
- Conditions
- Health Condition 1: K801- Calculus of gallbladder with othercholecystitis
- Registration Number
- CTRI/2022/08/044706
- Lead Sponsor
- Bankura Sammilani Medical College
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients belonging to ASA Grade I and ASA Grade II and posted for laparoscopic cholecystectomy.
Exclusion Criteria
Patients not willing to give consent, with anticipated difficult airway, history of known allergy to study drug, with labile blood pressure, severe renal disease, endocrine and cardiac dysfunction, patients on drugs like beta-blockers that has drug interaction with study drugs, patients with Lambert Eaton syndrome and myasthenia Gravis, patients with history of chronic alcoholism or drug abuse, patients who are pregnant or lactating mothers are excluded from study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method When both magnesium sulphate and dexmedetomidine will be used at the same moment of anaesthesia in the proposed study one drug is expected to come out with superior efficacy than the other in attenuating haemodynamic changes associated with laparoscopic cholecystectomy.Timepoint: 1hour to 2hours (duration of the particular surgery)
- Secondary Outcome Measures
Name Time Method To assess the changes in heart rate and blood pressure during endotracheal intubation and endotracheal intubation.Timepoint: 10mins