Study to examine the causes and clinical impact of airway hypersecretion in patients with bronchial asthma or chronic cough
Not Applicable
- Conditions
- Bronchial asthma Chronic cough
- Registration Number
- JPRN-UMIN000004068
- Lead Sponsor
- Kyoto University Graduate School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
Not provided
Exclusion Criteria
1)Patients who had upper respiratory infection within previous 8 weeks 2)Patients who treated with systemic corticosteroids within previous 4 weeks 3)Patients who smoked within previous 6 months or had smoked more than 5 pack-years in the past 4)Patients who take inhaled corticosteroids, expectorants, antibiotics, antiallergy agents 5)Patients who have other respiratory diseases 6)Patients who are concidered inappropriate by physicians in charge
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Induced sputum mucin levels
- Secondary Outcome Measures
Name Time Method Relationships between induced sputum mucin levels and various clinical indices which are listed below 1)Exhaled nitric oxide levels 2)Indices of pulmonaly function 3)Indices of airway responsiveness 4)Indices of capsaicin cough sensitivity 5)Cell differentials and biomarkers of induced sputum 6)Scores of questionnaires