Skeletal outcome of Parathyroidectomy in patients with renal hyperparathyroidism

• Conditions: Bone mass densities comparison in renal hyperparathyroidism patients before and after total parathyroidectomy with parathyroid implantation; Renal hyperparathyroidism; Bone mass density; total parathyroidectomy with parathyroid implantation

• Registration Number: TCTR20211030001
• Lead Sponsor: /A

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-10-30
• Study Completion: 2021-12-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending (Not yet recruiting)
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

Chronic kidney disease patients with serum PTH more than 1000 pg/ml for 2 times consecutively after medication with hypercalcemia, hyperphosphatemia that can not be controlled with medications
Renal hyperparathyroidism patients: Chronic kidney disease patients with elevated PTH resulting from hypercalcemia with low 1,25-dihydroxy-vitamin D3 level
Have bone mass density result before total parathyroidectomy with parathyroid implantation
Underwent total parathyroidectomy with parathyroid implantation at least 6 months before bone mass density test
18-90 years old

Exclusion Criteria

Hypercalcemia 6 months after total parathyroidectomy with parathyroid implantation

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Bone mass density at 6 months after end of the intervention T-score or Z-score

Secondary Outcome Measures

Name	Time	Method
Parathyroid hormone at 6 months after end of the intervention Parathyroid hormone level,serum calcium at 6 months after end of the intervention serum calcium level,serum phosphate at 6 months after end of the intervention serum phosphate level