Comparison of two diagnostic tests, EEG and Neuroimaging) in the evaluation of children with seizures
- Conditions
- Health Condition 1: null- Neurologically Normal Children With First Episode of Afebrile Seizures
- Registration Number
- CTRI/2013/05/003673
- Lead Sponsor
- ESI Hospital and Postgraduate Institute of Medical Sciences Research ESIPGSMR
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 170
•Presenting to the Pediatric department of ESI hospital with first episode of unprovoked, afebrile generalized tonic clonic or tonic, or partial seizures (or suspected seizures)
•Neurologically normal children
No development delay on history and no evidence of Neuroregression
Normal head circumference
No abnormal neurological findings
Normal fundus examination
1. Status epilepticus;
2. Seizures associated with
oan acute CNS infection (e.g., meningitis, encephalitis),
ohead injury, or
osystemic illness known to be associated with seizures (e.g., Shigella encephalopathy, SSPE);
3. Admitted for a suspicion of seizure but discharged with an alternated diagnosis e.g., breath-holding spell, pseudoseizure;
4. Recognizable dysmorphism or neurocutaneous syndrome; and
5. Persistent alteration of mental status or failure to return to baseline after the seizure
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method â?¢Proportion of investigations having clinically relevant information (CRI) in children evaluated initially with neuroimaging OR EEG.Timepoint: Four weeks
- Secondary Outcome Measures
Name Time Method â?¢Etiologies of first afebrile seizure in children <br/ ><br>â?¢Time taken to schedule the investigations in children with FAS <br/ ><br>â?¢Number of hospital visits made for investigative workup of FAS <br/ ><br>â?¢Adverse events associated with investigations in children with FAS <br/ ><br>Timepoint: Four weeks