Virus Allianz NRW Standort Bonn Study

• Conditions: U07.1; COVID-19, virus identified

• Registration Number: DRKS00031836
• Lead Sponsor: Institut für Virologie/Universitätsklinikum Bonn

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-08-09
• Study Completion: 2023-09-30
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 675

Inclusion Criteria

Consenting residents of Heinsberg or Rheinbach and prior participation in at least one of the two studies DRKS00021306 or DRKS00023113 or random selection by the local government based on resident data.

Exclusion Criteria

(i) Refusal of informed consent.
(ii) Contraindication to the selected specimen collection methods (venipuncture or capillary blood collection via fingertip or throat swab).

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Prevalence of SARS/CoV-2 positive participants in the study population, defined as the number of participants with a positive laboratory result (from at least one of the media sampled in the study) divided by the total number of study participants at each survey time point.

Secondary Outcome Measures

Name	Time	Method
(i) Incidence of new infections as the proportion of participants with a positive laboratory result (from at least one of the specimens collected in the study) with a previous negative SARS-CoV2 IgG/PCR result (3-month incidence).<br>(ii) Incidence of reinfection in the population determined by the proportion of participants with a repeat positive swab result with a previous positive SARS-CoV2 IgG/PCR result.<br>(iii) Determination of the progression of antibody titers over a defined period of time.<br>(iv) Infection rate, defined as the number of participants with new positive laboratory findings (per study section) divided by the total number of study participants and per time period.<br>(v) comparison of symptoms recorded in the questionnaire over time and between infection events<br>(vi) Comparison of exposure of infected and uninfected participants to personal and behavioral factors.