Clinical comparative study for efficacy of jatyadi ghrita with jeerak ghrita as an external application in the management of agnidagdha vrana (second degree burn)
- Conditions
- Burns and corrosions of external body surface, specified by site. Ayurveda Condition: AGNIDAGDHAH,
- Registration Number
- CTRI/2025/06/088980
- Lead Sponsor
- SHRIKANT RUKHMANRAO GAIKWAD
- Brief Summary
Ayurveda has mentioned various principles and treatment modalities for the prevention as well as cure for the disease. It is mentioned as aim of Ayurveda.
Ashtanga Ayurveda has mentioned eight different branches of Ayurveda which includes Shalya Tantra which deals with various disorders like anorectal, etc.
The description of types, clinical features, treatments and complications of Dagdha Vrana written in Ayurveda classics are quite similar to burn injury describe in modern medicine.
In Ayurvedic classics use of medicinal, surgical and para surgical modalities for treatment of different ailments are given. Para surgical procedures like Agnikarma, Ksharakarma and Raktamokshana were commonly used by Ayurvedic physicians. During the therapy like Agnikarma there were accidental burn injuries known as ‘Pramada Dagdha’ or ‘Ittartha Dagdha’.
Burn is critical skin condition to care due to involvement of many factor such as skin layers, inflammation and pain. From ancient days it is serious health issue. It is having high mortality rate in the whole world, injuries caused by burns have many more complications like cosmetic disfigurement permanent physical damage and mental trauma.
Degree of Burn are classified according to its depth ; which includes Superficial 1st degree, superficial 2nd degree, deep 2nd degree, 3rd degree and 4th degree. Here in this study, Second degree superficial burn will be selected for the study. It includes blisters, moist wet, blanches with pressure severe pain to touch. It heals in 7-21 days. Its management includes cleansing, topical agent and sterile dressing.
Need of the study
The majority of the patients had third-degree burns followed by second-degree and first-degree burns. World wide.Flame and scald burns were the most common causes in all burn degrees.
Dagdha vrana are very frequently and commonly seen in society which are difficult to heal and leads to the intolerable painful condition to the subject. The ayurvedic management leading to better post healing scar reducing cost and hospital stay with nil complications
The management of wounds was explained under Shashti Upakrama, application of Ghrita is one among them. Now a days silver sulfadiazine is commonly used in burn but this doesn’t avoid post burn complications, affected patients may land into horribly contracted pigmented scar.
Jeeraka Ghrita is described by Bhaishajya Ratnawali as combination for having of burn wounds reduces the burn discharge and reduce burning sensation of burn area and blister formation. It contains Jeeraka, Ghrita, Rala, Moma and Jala. All this having Vranaghna, Vrana Ropana, Vrana Shodhana properties.
Jatyadi Ghrita is one of the known formulation used for the management of Vrana or wound healing. It contains Jati, Patol patra, Nimba patra, Haridra etc. all this contains having antimicrobial, analgesic, wound healing properties.
Here in this study, comparative study of Jeeraka Ghrita and Jatyadi Ghrita will be selected. All this drugs are easily available, easy to apply, affordable, cheap. Therefore, it will be selected for the comparative study.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- All
- Target Recruitment
- 60
- 1.Patients having Agnidagdh vrana superficial second degree burn and second degree burn will be salected.
- patients of age between 18 to 70 year were taken.
- salection of patient will be done irrespective of Sex, socioeconomic class, religion.
- 4.Extent the burn will be decided with the help of Rule of Nine through which the percentage of damage of surface area and depth can be estimated.
- Patients up to 20% burn.
- Patients first degree burn.
- Accidentally burn.
- patients with more than 20% burn area.
- Deep burn and vital organs area involved.
- electric burn.
- patients below ahe 18 year and above 70 year patient.
- patients suffering from HIV, HBsAg,AIDS.
- 6.ALL OTHER THAN INCLUSIVE CRITERIA.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method COMPARE EFFICACY OF JATYADI GHRITA AND JEERAK GHRITA AS AN EXTERNAL APPLICATION IN MANEGEMENT OF AGNIDAGDH VRANA(SECOND DEGREE BURN) BY USING SUBJECTIVE AND OBJECTIVE CRITERIA TOTAL DURETION OF MEDICATION -21 DAYS
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
ASHVIN RURAL AYURVED COLLEGE MANCHI HILL SANGAMNER
🇮🇳Ahmadnagar, MAHARASHTRA, India
ASHVIN RURAL AYURVED COLLEGE MANCHI HILL SANGAMNER🇮🇳Ahmadnagar, MAHARASHTRA, IndiaSHRIKANT RUKHMANRAO GAIKWADPrincipal investigator9370321097shrikantgaikwad2002@gmail.com