Comparative Clinical study of Wild and Cultivated Varieties of Ashwagandha for Grivastambha.

Completed

• Conditions: Other specified acquired deformities of musculoskeletal system. Ayurveda Condition: GRIVASTAMBAH/GRIVAHUNDANAMÂ (KEVALAVATA),

• Registration Number: CTRI/2021/02/031372
• Lead Sponsor: Government Ayurved Hospital Vadodara

Brief Summary

This study was randomized clinical trial to evaluate and compare the effects of different varieties of Ashwagandha (Withania somnifera Dunal) in Grivastambha. Total 28 patients were enrolled in 4 groups on the basis of computer-generated randomisation. From those, 24 patients had completed study. In this study powder of four varieties of Ashwagandha was applied with lukewarm water on affected part as a Lepa following Katu Taila Abhyanga twice in a day for 14 days*.* All four varieties of Ashwagandha showed statistically significant difference in various symptoms after treatment. Any ADR was not observed. Highest overall effect of therapy (68.67%) was achieved through Gujarat Anand Ashwagandha-1, while lowest in Nagori Ashwagandha (42.26%). Though, any statistically significant difference was not found among all four varieties of Ashwagandha. Thus, primary outcome that Ashwagandha is effective on Grivastambha was achieved. Along with that secondary outcome was also achieved as difference in clinical efficacy of all four varieties of Ashwagandha on Grivastambha.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-01-05
• Last Update Posted: 2023-09-20

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 6

Inclusion Criteria

• Clinical symptoms of Grivastambha with or without radiological changes.
• Pain in the neck Stiffness of neck Difficulty in neck movements (Minimum 3 symptoms) Symptomatology of Grivastambha (cervical spondylosis) for more than 3 months or in recurrent phase.

Exclusion Criteria

<25 Years or >50 Years Any acute/ infectious disease Chronic disease (SLE, rheumatoid diseases, ankylosing spondilitis) Stenosis of the spinal canal Fibrositis Unwilling to participate in the trial.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in the Classical Symptoms of Grivastambha	21 days

Secondary Outcome Measures

Name	Time	Method
Difference in Clinical efficacy of Cultivated Medicinal Plants Varieties	21 Days

Trial Locations

Locations (1)

Government Ayurved Hospital, Vadodara; 🇮🇳 Vadodara, GUJARAT, India

Government Ayurved Hospital, Vadodara

🇮🇳Vadodara, GUJARAT, India

Dr Vinita A Khatri

Principal investigator

8487012556

vinitakhatri31@gmail.com