Skip to main content
Clinical Trials/NL-OMON43812
NL-OMON43812
Completed
Not Applicable

Aortic Stenosis * Identification of high-risk valve pathology using STRESS physiology (AoS-STRESS) - AoS-STRESS

Catharina-ziekenhuis0 sites50 target enrollmentTBD

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
aortic valve stenosis
Sponsor
Catharina-ziekenhuis
Enrollment
50
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
2 years ago
Study Type
Observational invasive

Investigators

Eligibility Criteria

Inclusion Criteria

  • \-Age \* 18 years.
  • \-Undergoing TAVI or balloon valvuloplasty for standard clinical indications/undergoing coronary catheterization and have had an echo with a moderate aortic stenosis in the last 3 months
  • \-Ability to understand and the willingness to sign a written informed consent.

Exclusion Criteria

  • \-Unrevascularized and severe coronary artery disease (for example a 90% diameter stenosis or FFR\<0\.7 in the proximal left anterior descending artery) that in the opinion of the primary TAVI/BAV operator would produce significant ischemia during dobutamine infusion.
  • \-Significant aortic regurgitation, mitral valve disease, tricuspid regurgitation, or intracardiac shunt that would invalidate thermodilution cardiac output or the interpretation of transvalvular flow across the aortic valve.
  • \-Co\-existing hypertrophic cardiomyopathy.
  • \-Atrial fibrillation or tachycardia with rapid ventricular response, a history of significant ventricular tachycardia or fibrillation, or an implanted cardiac defibrillator whose treatment thresholds would be reached during dobutamine infusion.
  • \-Known hypersensitive response to dobutamine.
  • \-Recent (within 3 weeks prior to cardiac catheterization) ST\-segment elevation myocardial infarction (STEMI) in any arterial distribution.

Outcomes

Primary Outcomes

Not specified

Similar Trials