Radical Versus Conservative Surgery in Liver Cystic Echinococcosis: a Prospective Cohort Study in a High-volume Western Centre

Completed

• Conditions: Liver; Cyst, Hydatid, Granulosus (Etiology)

• Registration Number: NCT06570876
• Lead Sponsor: Hospital Universitari de Bellvitge

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-8-22
• Last Update Posted: 2 September 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 192

Inclusion Criteria

Inclusion Criteria:<br><br> - Adult population (18 years or older) of both sexes surgically intervened for a<br> diagnosis of LCE at the Bellvitge University Hospital and during the period<br> described using a conservative or radical technique.<br><br> - Patients with asymptomatic liver hydatid cysts of active type or transition CE1 to<br> CE3 according to the WHO classification.<br><br> - Patients with symptomatic or complicated hepatic hydatid cysts of any type (CE1 to<br> CE5) according to the WHO classification.<br><br>Exclusion Criteria:<br><br> - Patients under 18 years of age.<br><br> - Patient operated on for LCE diagnosis with inactive asymptomatic cysts (CE4 or CE5<br> according to the WHO classification).<br><br> - Patients with less than 1 year of follow-up.

Exclusion Criteria

Not provided

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To assess the incidence of liver recurrence between the RS and the CS groups, identifying potential risk factors;To evaluate the incidence of postoperative biliary fistula between the RS and the CS groups, identifying possible risk factors.

Secondary Outcome Measures

Name	Time	Method
To estimate the incidence of overall morbidity related to surgery.;To estimate the incidence of specific morbidity related to surgery.;To specifically analyze the incidence of postoperative biliary fistula and complex biliary fistula, and identify possible risk factors.;To estimate the incidence of mortality related to surgery.;To estimate the rate of hepatic and extrahepatic recurrence (number of disease-free months)