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Radical Versus Conservative Surgical Treatment of Liver Hydatid Cysts

Completed
Conditions
Hydatid Cyst
Registration Number
NCT04988958
Lead Sponsor
Université de Sousse
Brief Summary

The management of liver hydatid cysts (LHC) is controversial. Surgery remains the basic treatment, and can be divided into radical and conservative approaches. The purpose of this study was to compare the outcome of radical and conservative surgery (CS) in the treatment of LHC and to evaluate the efficiency and safety of radical surgery (RS).

Detailed Description

The management of liver hydatid cysts (LHC) is controversial. Surgery remains the basic treatment, and can be divided into radical and conservative approaches. The purpose of this study was to compare the outcome of radical and conservative surgery (CS) in the treatment of LHC and to evaluate the efficiency and safety of radical surgery (RS).

Data from all patients with LHC treated in Sahloul Hospital, between January 2000 and December 2019, were retrieved from a retrospective database. To minimize selection bias, propensity score matching (PSM) was performed, based on variables representing patient characteristics and operative risk factors.

RS especially total pericystectomy had fewer postoperative complications and lower recurrence rate compared to CS. RS may be the preferred procedure for LHC if the expertise is available.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
914
Inclusion Criteria
  • age over 14 years old.
  • Patients presenting liver hydatid cyst .
Exclusion Criteria
  • age less than 14 years old.
  • Patients presenting other localization of hydtic cyst , than the liver.
  • calcified cysts.
  • patients with incomplete medical records.
  • patients who were lost to follow up.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
recurrence of hydatic cyst2 years

recurrence of hydatid cyst after surgery

Secondary Outcome Measures
NameTimeMethod
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