Surgical Treatment of Hepatic Hydatidosis in Elderly Patients

Completed

• Conditions: Cystic Echinococcosis
• Interventions: Other: Surgical remove

• Registration Number: NCT05113550
• Lead Sponsor: Universidad de Extremadura

Brief Summary

Cystic echinococcosis is a clinically complex chronic parasitic disease and a major socioeconomic problem in endemic areas. The safety of liver resection in elderly patients is often debated among medical professionals. The investigators analyzed the postoperative morbidity and mortality rates of elderly patients who underwent surgery at our unit.

Detailed Description

Retrospective observational study from prospective database focused on liver hydatidosis carried out at our Hepato-Pancreato-Biliary Surgery Unit. The study period spanned from January 2006 to October 2020. The study was approved by the Research Ethics Committee of our hospital. An informed consent from the patient was not required since the study was retrospective and observational, and entailed no risk. Seventy years of age was the cutoff age to consider patients as elderly.

Inclusion criteria of patients: liver hydatid cyst (LHC) diagnosed by preoperative computed tomography (CT) or magnetic resonance imaging (MRI) and pathological diagnosis after surgery, and LHC treated by total or partial pericystectomy.

Exclusion criteria of patients: emergency surgery and simple drainage of cyst.

Study Timeline

• Study Start: 2021-01-01
• Primary Completion: 2021-09-30
• Study Completion: 2021-09-30
• Status Verified: 2021-10
• Study First Submitted: 2021-10-28
• Study First Submitted QC: 2021-10-28
• Last Update Submitted: 2021-11-08
• Study First Posted: 2021-11-09
• Last Update Posted: 2021-11-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 279

Inclusion Criteria

• liver hydatid cyst (LHC)
• pathological diagnosis after surgery
• LHC treated by total or partial pericystectomy

Exclusion Criteria

• emergency surgery and simple drainage of cyst

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Young group	Surgical remove	patients \< 70 years of age
Elderly	Surgical remove	Patients ≥ 70 years of age)

Primary Outcome Measures

Name	Time	Method
Morbidity	90 days	Patients with postoperative morbidity according to the Clavien-Dindo score 19, "severe complication" (Clavien-Dindo ≥ IIIa) and postoperative mortality

Trial Locations

Locations (2)

Universidad de Extremadura- Facultad de Medicina; 🇪🇸 Badajoz, Spain

Gerardo Blanco-Fernández; 🇪🇸 Badajoz, Spain