CTRI/2024/12/077997尚未招募不适用
Comparing the effectiveness of ultrasound guided 5 percent dextrose prolotherapy versus platelet rich plasma in treatment of moderate to sever carpal tunnel syndrome- randomised control trial
未提供1 个研究点 分布在 1 个国家目标入组 48 人开始时间: 2024年12月25日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 48
- 试验地点
- 1
- 主要终点
- NUMERIC PAIN RATING SCALE
研究概览
简要总结
| Carpal tunnel syndrome (CTS) is the most common |
| peripheral entrapment neuropathyis thought to be caused by the compression of the median nerve as a result of excess pressure from surrounding tissues leading to nerve ischemia within the carpaltunnel.Therefore, applying a novel nonsurgical |
| management is important and valuable duringthe presurgical stage in |
| patients with CTS, especially those of moderate-to-severe grades. Perineural |
| injection therapy is a technique involves the injection of 5% dextrose |
| (osmolality similar to that of normal saline) solution near the peripheral |
| nerve and has been found to provide promising pain-relief benefits. Platelet-rich plasma (PRP) is a biologic product |
| of concentrated platelets; it contains several growth factors well known to |
| be effective on inflammation and wound healing.5% Dextrose and platelet-rich plasma (PRP) are |
| the two most commonly used regenerative injection have shown their potential |
| role in promoting tissue |
repair.
AIM - To comparing the effectiveness of ultrasound guided 5% dextrose prolotherapy versus platelet rich plasma in treatment of moderate to severe carpal tunnel syndrome.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 20.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Moderate to severe carpal tunnel sydrome based on nerve conduction study with symptoms persisting for more than one month.
排除标准
- •Polyneuropathy Wrist surgery Inflammatory arthritis Hypothyroid Pregnancy Rheumatoid diseases Diabetes mellitus Trauma/Neoplasm/Infection at injection site.
结局指标
主要结局
NUMERIC PAIN RATING SCALE
时间窗: 0, 1, 3, 6 months
次要结局
- BOSTON CARPAL TUNNEL QUESTIONNAIRE and(NERVE CONDUCTION STUDY)
研究者
Dr Sumiya Begam U
Tamil Nadu Dr MGR Medical University
研究点 (1)
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