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临床试验/CTRI/2024/12/078573
CTRI/2024/12/078573尚未招募2/3 期

Comparison of efficacy in ultra sound guided versus blind corticosteroid injection for carpal tunnel syndrome

R. G. Kar Medical College, Kolkata1 个研究点 分布在 1 个国家目标入组 52 人开始时间: 2025年1月15日最近更新:

试验速览

阶段
2/3 期
状态
尚未招募
发起方
入组人数
52
试验地点
1
主要终点
To assess if any possible outcome difference in the process of corticosteroid injection

研究概览

简要总结

The most common entrapment neuropathy in the upper limbs is carpal tunnel syndrome (CTS). CTS is brought on by compression of the median nerve in the wrist while passing through the carpal tunnel. Compression of the nerve causes ischemia which leads to nerve damage and impairs its ability to function properly. Multiple options exist for treatment, which may be widely divided into two categories: surgical intervention and non-surgical intervention. Both blind and ultrasound guided injections of steroids into the wrist frequently work. This study is to evaluate and compare the effectiveness between US guided injection of corticosteroid and blind injection of corticosteroid in the management of CARPAL TUNNEL SYNDROME(CTS). It will be a prospective randomized control study and will be conducted in the department of Physical Medicine and Rehabilitation in R.G.KAR. Medical College and Hospital, Kolkata, West-Bengal. Sample size calculated was 52 i.e. 26 participants in each group. Symptomatic severity and functional severity will be measured using Boston Carpal Tunnel Questionnaire (BCTQ) symptom severity scale and function severity scale respectively at 4 weeks and 12 weeks post intervention and neurological outcome will  be measured using SNAP (Sensory Nerve Action Potential), SNCV (Sensory Nerve Conduction Velocity).

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
Investigator Blinded

入排标准

年龄范围
18.00 Year(s) 至 70.00 Year(s)(—)
性别
All

入选标准

  • 1.Age group: 18 – 70 years 2.Both the genders.
  • (males, females and others) 3.Diagnosed cases of CTS (Carpal Tunnel Syndrome).

排除标准

  • Cases with previous carpal tunnel syndrome Cases with history of previous corticosteroid therapy Pregnancy Cases with psychiatric history Cases with peripheral polyneuropathy like in diabetes Cases with history of traumatic nerve injury Focal nerve entrapment other than CTS Rheumatoid arthritis Hypothyroidism Cases refusing to carry forward with the study Cases with any substance abuse addiction history.

结局指标

主要结局

To assess if any possible outcome difference in the process of corticosteroid injection

时间窗: Day0, Day28, Day84

by US guided method in one group and blind method in the other group by using the BCTQ

时间窗: Day0, Day28, Day84

(Boston Carpal Tunnel Questionnaire)

时间窗: Day0, Day28, Day84

次要结局

  • To assess if any possible outcome difference in the process of corticosteroid injection(by US guided method in one group and blind method in the other group by using the SNAP)

研究者

发起方
R. G. Kar Medical College, Kolkata
申办方类型
Government medical college
责任方
Principal Investigator
主要研究者

Dr Ayan Baur

R. G. Kar Medical College And Hospital

研究点 (1)

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