Investigation of the Effectiveness of Diadynamic Current in Patients With Carpal Tunnel Syndrome
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 80
研究概览
简要总结
Carpal tunnel syndrome (CTS), first described by Paget in 1854, is the most common entrapment neuropathy. Conservative treatment approaches are prioritized in patients with mild to moderate CTS. Conservative management includes education, tendon and median nerve gliding exercises, physical therapy modalities, kinesiotaping, manual therapy techniques, injection options, and oral medical treatments. First-line treatment generally consists of education, exercise, and splinting.
Tendon and median nerve gliding exercises represent key components of conservative treatment. Splinting is recommended at all stages of CTS, with wrist splints designed to maintain a neutral position being the most commonly preferred option. The prevailing approach in the literature supports the use of splints primarily during nighttime.
Diadynamic current (DDC) is considered to have a composite analgesic mechanism, primarily explained by the gate control theory. Additional mechanisms suggest that DDC affects both sensory and motor nerves and may increase endorphin release, contributing to pain relief. A single treatment session typically does not exceed 12 minutes. Some studies indicate that the analgesic effect of DDC may be greater than that of transcutaneous electrical nerve stimulation (TENS). Although TENS is widely used in physical therapy and rehabilitation practice, DDC may represent a realistic alternative for clinical pain management.
The aim of the study is to evaluate the effect of diadynamic current therapy on clinical symptoms in patients with CTS and to investigate its impact on electrophysiological findings of the median nerve.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Clinically and electrophysiologically diagnosed with carpal tunnel syndrome (CTS)
- •Provision of informed consent
- •Age between 18 and 65 years
排除标准
- •Age below 18 years or above 65 years
- •Median nerve distal motor latency > 6.0 ms on nerve conduction studies (NCS)
- •Thenar muscle atrophy
- •History of carpal tunnel syndrome surgery
- •History of steroid injection into the carpal tunnel
- •History of physical therapy for CTS within the past 6 months
- •Cervical radiculopathy
- •Tenosynovitis in the ipsilateral upper extremity
- •Other compressive neuropathy in the ipsilateral upper extremity
- •Peripheral polyneuropathy
- •History of trauma or fracture involving the hand, wrist, or forearm
- •Pregnancy
- •Presence of metabolic disease
- •Inflammatory rheumatic disease
- •Acute and/or chronic renal failure
- •Severe cognitive impairment preventing understanding and following simple instructions
- •Severe visual or hearing impairment preventing participation in treatment
- •Current use of pregabalin or gabapentin
- •Systemic diseases (e.g., diabetes mellitus, hypothyroidism, rheumatic diseases)