China Red Eye Study on Allergic Conjunctivitis

• Conditions: Allergic Conjunctivitis

• Registration Number: NCT03812952
• Lead Sponsor: Sun Yat-sen University

Brief Summary

This study is the first multi-center cross-sectional study on the diagnosis and misdiagnosis of allergic conjunctivitis in the ophthalmology clinic in China. It provides a clinical basis for the standardized diagnosis and treatment of allergic eye diseases.

Detailed Description

Allergic conjunctivitis is a common disease in ophthalmology. The European Allergy Association, Japan, the United States and other countries have clear diagnostic criteria or guidelines for the definition and diagnosis of allergic diseases and allergic conjunctivitis. However, China is currently lacking related guidelines. Allergic conjunctivitis has some of the same symptoms and signs as other infections/non-infectious conjunctival inflammation. When the symptoms and signs are atypical, it is prone to missed diagnosis and misdiagnosis, resulting in prolonged disease duration, drug abuse and waste of medical resources.

The current abuse of antibiotics is considered to be a huge problem in the treatment of ocular surface diseases. A study in our country believes that the rate of misdiagnosis of dry eye is as high as 66.2%, and most of them are misdiagnosed as chronic conjunctivitis, resulting in frequent using a variety of antibiotic eye drops. At present, the misdiagnosis of allergic conjunctivitis and the abuse of antibiotics caused by misdiagnosis in China are still unclear, therefore clinical research is urgently needed. We intend to use this study to understand the status of diagnosis and treatment of allergic conjunctivitis in China, and provide clinical evidence for the standard diagnosis and treatment of allergic eye diseases.

Study Timeline

• Study Start: 2018-08-01
• Study First Submitted: 2018-11-08
• Status Verified: 2019-01
• Study First Submitted QC: 2019-01-20
• Last Update Submitted: 2019-01-20
• Study First Posted: 2019-01-23
• Last Update Posted: 2019-01-23
• Primary Completion: 2019-12-31
• Study Completion: 2019-12-31

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 3000

Inclusion Criteria

• Patients whose clinical diagnosis is allergic conjunctivitis.

Exclusion Criteria

• The investigator believes that there are any unsuitable reasons for participating in the trial.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Specific diagnosis of the patients	Until the study completion, up to 1 year	the investigators record the patients' specific diagnosis (such as seasonal allergic conjunctivitis, perennial allergic conjunctivitis, vernal keratoconjunctivitis，and etc) on questionnaire when the patient come

Trial Locations

Locations (1)

Zhongshan Ophthalmic Center of Sun yat-sen Universtiy; 🇨🇳 Guangzhou, Guangdong, China