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DEKSEL Nano Syrup [Vitamin D 6000IU/5mL] in patients with Major Depressive Disorder

Phase 2
Conditions
Health Condition 1: F330- Major depressive disorder, recurrent, mild
Registration Number
CTRI/2020/12/030020
Lead Sponsor
Pulse Pharmaceuticals Pvt Ltd
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1.Patients suffering from mild to severe depression.

2.18â??65 Years of age, of either gender.

3.Willing to give signed Informed Consent.

Exclusion Criteria

1.Patients suffering from bipolar affective disorder, any form of schizophrenia, tuberculosis, and sarcoidosis.

2.Pregnant or lactating women.

3.Intake of more than 10 μg vitamin D daily.

4.Known allergy, intolerance or contraindication to study medication.

5.Women of childbearing potential not willing to utilize effective contraception. A negative human chorionic gonadotropin (HCG) pregnancy test is required.

6. Patients were excluded if they at baseline had: serum 25(OH)D <10 nmol/L or >100 nmol/L, serum calcium (ionized) >1.40 mmol/L, estimated glomerular filtration rate (eGFR) <60 mL/min/1.72 m2, serum phosphate <1.50 mmol/L (females) and <1.60 mmol/L (males aged between 18-49 years) or <1.35 mmol/L (males >49 years), or serum parathyroid hormone (PTH) >9.2 pmol/L.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The primary outcome will be assessed using HAM-D17 and MADRSTimepoint: At baseline, 12 weeks
Secondary Outcome Measures
NameTimeMethod
1.Clinicians Global Impressions (CGI) Score <br/ ><br>2.Incidence of adverse events. <br/ ><br>Timepoint: 90 DAYS
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