A prospective randomised trial on the palatability and efficacy of Coca-Cola Zero® versus water for polyethylene glycol bowel preparation before colonoscopy
Completed
- Conditions
- Digestive SystemPalatability, safety, and efficacy of Coca-Cola Zero as a solvent for polyethylene bowel preparation for colonoscopy
- Registration Number
- ISRCTN18516614
- Lead Sponsor
- Seow-Choen Colorectal Centre Pte Ltd (Singapore)
- Brief Summary
1. 2016 results in https://www.ncbi.nlm.nih.gov/pubmed/26682533 (added 29/01/2019)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 200
Inclusion Criteria
1. Adults over 21 years old
2. Healthy or with mild or well controlled chronic illnesses. Control of systemic disease was determined on the basis of no increase in medication or development of new symptoms or complications within the past year
3. Scheduled for an elective colonoscopy at our institution
Exclusion Criteria
1. Pregnant patients
2. Patients with suspected intestinal obstruction
3. Patients at risk of aspiration
4. Patients with serious systemic or poorly controlled chronic illnesses
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The palatability of the PEG+Coke solution compared to the PEG+water solution. Palatability was judged based on a four-point questionnaire which was issued to the patient prior to discharge.
- Secondary Outcome Measures
Name Time Method <br> 1. Cleanliness of the bowel preparation was judged by the endoscopist as well as two endoscopy nurses during the colonoscopy<br> 2. Adverse reactions, willingness to repeat the same solution again or recommend it to a friend were measured based on the same patient questionnaire prior to discharge after the endoscopy<br>