Climat Impact on Urinary Iodine Concentration
- Conditions
- Iodine Deficiency
- Interventions
- Other: Climate
- Registration Number
- NCT03215680
- Lead Sponsor
- Swiss Federal Institute of Technology
- Brief Summary
Urinary iodine concentration (UIC) is the recommended biomarker of iodine status in populations. Yet, the influence of climate on UIC remains unclear. Hot climate may reduce urine volume and consequently increase UIC independent of iodine status. This could lead to an overestimation of population iodine intake, thus masking iodine deficiency in vulnerable groups.
In this longitudinal observational cohort study in women of reproductive age we will collect 24h and spot urine samples in the summer and winter season. The influence of high temperature climates on UIC, measured and estimated urinary iodine excretion will be estimated.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 363
Not provided
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Tanzanian Women of Reproductive Age Climate Healthy women of reproductive age living in Tanzania in an area with hot and temperate climate South African Women of Reproductive Age Climate Healthy women of reproductive age living in South Africa in an area with hot and temperate climate
- Primary Outcome Measures
Name Time Method Urinary iodine concentration 6 months Measured in 24h urine collections
- Secondary Outcome Measures
Name Time Method Urinary iodine excretion 6 months Measured in 24 h urine collections
Trial Locations
- Locations (2)
Centre of Excellence for Nutrition, Faculty of Health Science, North West University
🇿🇦Potchefstroom, South Africa
Ministry of Health, Community Development Gender, Elderly and Children
🇹🇿Dar es Salaam, Tanzania