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临床试验/NCT06138886
NCT06138886已完成不适用

Calisthenics Exercise Program and Pulsed Electromagnetic Therapy on Liver Function Following Burn Injuries.

Cairo University2 个研究点 分布在 1 个国家目标入组 90 人开始时间: 2023年11月14日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
90
试验地点
2
主要终点
Concentration of Alanine transaminase (ALT) and Aspartate transaminase(AST) enzymes in blood plasma.

研究概览

简要总结

Serum concentrations of alanine transaminase (ALT) and aspartate transaminase (AST) significantly increased immediately upon burn trauma and remained significantly elevated for about three years.

Calisthenics exercises consist of movements that increase the flexibility and strength of the body. It is a type of exercise consisting of various movements applied without equipment and apparatus, using your body weight.

Clinical evidence shows that PEMF therapy reduces pain associated with trauma from accidents, sports injuries, surgeries and burns as well as from disease and degeneration. PEMF therapy improves these conditions in many different concurrent ways including mechanical, chemical, electrical and magnetic processes within the cells of the body.

详细描述

-Measurement procedures: Serum blood draws will be taken by certified technicians with the participant in a seated position.

Spectrophotometry is the measurable analysis technique using electromagnetic spectra. It deals with the ranges of wavelengths such as near ultraviolet, near-infrared and visible light. A device called a spectrophotometer is used to measure the absorbance or transmittance through a liquid sample. The spectrophotometer measures a specific wavelength and it is possible to choose any wavelength in the spectrophotometer register as the double beam sends a beam through a blank reference sample and one through the sample to be measured.

Normal values that will be used for patients are 0-45 IU/l for Alanine transaminase (ALT) and 0-35 IU/l for Aspartate transaminase(AST).

Measurements will be taken before the treatment (pre-treatment) and after 3 months (post-treatment).

2-Therapeutic procedures: 2. a: Procedures of calisthenics exercises program: The workout schedule will last for 12 weeks with medium-intensity calisthenics exercises of 60 minutes for 3 days in a week. The intensity will be held at the pace at which the participants feel comfortable. In each workout period, after 10 minutes of warm-up, the exercises will be done in 45 minutes as pistol squat, leg raise, lunge stop, Russian twist, shoulder taps, inverse pull-up, dips, supermen exercise and crunch for 3 sets/8 repetitions and plank exercise for 3 sets/30min. Every workout will end with 5 minutes of cooling exercises.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Double (Participant, Investigator)

入排标准

年龄范围
20 Years 至 45 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Age ranges between 20-45 years.
  • Male and female patients will participate in the study.
  • All patients have burns with BBSA about 30% to 50%
  • All patients enrolled on the study will have their informed consent

排除标准

  • Cardiac diseases.
  • Burn of the sole of foot.
  • Exposed hand or foot tendons.
  • Upper or Lower limb amputation.
  • History of liver diseases.
  • Body mass index (BMI=kg/cm2)<30%.

结局指标

主要结局

Concentration of Alanine transaminase (ALT) and Aspartate transaminase(AST) enzymes in blood plasma.

时间窗: Three months

Liver enzymes

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Aya Gamal Fawzy El-Sayed

Lecturer of physical therapy of surgery

Cairo University

研究点 (2)

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