NCT00178295已完成不适用
Radiation-Induced Cytokine Cascades and Their Correlation With Central Nervous System Injury
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 44
- 试验地点
- 1
- 主要终点
- Change from baseline in Cytokine blood levels
研究概览
简要总结
Treatment for brain cancer may include radiation therapy. Radiation therapy is the treatment of tumors with X-rays. This study is related to understanding the side effects of radiation treatment for brain tumors.
This study is being conducted by the University of Rochester Cancer Center to compare the extent of side effects of brain cancer treatment with changes in levels of blood proteins called cytokines.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Any patient who will be treated to the brain or spinal axis for a CNS tum Patients so treated will be stratified according to whether or not the hypo is included in the treatment fields.
- •Patients receiving external beam radiation to the brain may also be rece chemotherapy or interferon-beta. (Add. #1, 11-9-95)
- •Patients receiving high dose rate (stereotactic radiosurgery) are eligible.
- •Patients must sign a study specific informed consent meeting all federal a guidelines.
- •Patients of any age, including children, are eligible (Add. #3, 11/25/97).
排除标准
- •Patients who have a malignancy involving the hypothalamic-pituitary ax
- •Patients who are not treated with irradiation to the brain or spinal axis.
结局指标
主要结局
Change from baseline in Cytokine blood levels
时间窗: 12 weeks from start of radiation
次要结局
未报告次要终点
研究者
Louis Constine
Principal Investigator
University of Rochester
研究点 (1)
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