Comparison between Midazolam and Dexmedetomidine in bronchoscopy
Not Applicable
- Conditions
- Health Condition 1: null- All patients in the age group 18 to 65 years requiring flexible bronchoscopy in the Department of Respiratory Medicine.
- Registration Number
- CTRI/2017/10/009969
- Lead Sponsor
- Kasturba Medical College Manipal
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
All patients in the age group 18 to 65 years requiring flexible bronchoscopy in the Department of Respiratory Medicine.
Exclusion Criteria
1.Patients with known or suspected allergy to Midazolam or Dexmedetomidine
2.Patients with renal or hepatic insufficiency
3.Patients with seizure disorder
4.COPD patients with FEV1 <50%
5.Patients with psychiatric disorder
6.Haemodynamically unstable patients including cardiac failure
7.Heart rate <50 beats per min or second or third degree heart block
8.Patients with body weight more than 70kg.
9.Pregnancy and lactation
10.Hypovolemia
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.Composite score during the bronchoscopy procedure. <br/ ><br>2.Numerical Rating Scale (NRS)for pain intensity and distress. <br/ ><br>3.Visual Analogue Scale for cough. <br/ ><br>4.Ease of bronchoscopy procedure. <br/ ><br>5.Ramsay sedation score. <br/ ><br>6.Post- procedure patient response after 24hours.Timepoint: Prior, during, 10mins after bronchoscopy and 24hours after bronchoscopy
- Secondary Outcome Measures
Name Time Method 1.Duration of bronchoscopy procedure. <br/ ><br>2.Number of doses of rescue medication required during the procedure. <br/ ><br>3.Haemodynamic variables such as Heart rate , systolic blood pressure, and diastolic blood pressure <br/ ><br>4.Oxygen saturation . <br/ ><br>5.Lignocaine dose used <br/ ><br>Timepoint: BASELINE,START OF FB,5 MINUTES AFTER THE START OF FB,10 MINUTES AFTER THE START OF FB,END OF FB,10 MINUTES AFTER THE END OF FB. <br/ ><br>