effects of midazolam and ondansetron on nausea and vomiting after spinal anesthesia
Phase 2
- Conditions
- post spainal nausea and vomiting.Other complications of anaesthesia
- Registration Number
- IRCT2017021112251N4
- Lead Sponsor
- Vice Chancellor for research of Hamadan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 80
Inclusion Criteria
Age 18-40 years and undergoing cesarean section; physical status class I or II in accordance with anesthesia; Term pregnancy (gestational age 36-40 weeks); Singleton pregnancy.
Exclusion criteria: High-risk pregnancy; Preeclampsia; A history of liver, Mental, renal, gastrointestinal disorders and motion sickness; history of hyperemesis gravidarum; The patients who received antiemetics during previous 24 hours; history of drug addiction; history of postoperative nausea and vomiting; Patients with spinal anesthesia ban.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ausea and vomiting. Timepoint: Since spinal anesthesia or intravenous of midazolam or ondansetron. Method of measurement: Nausea vomiting scale.;Nausea intensity. Timepoint: Since spinal anesthesia or intravenous of midazolam or ondansetron. Method of measurement: Visual analogue scale.
- Secondary Outcome Measures
Name Time Method Hemodynamic instability. Timepoint: during the surgery and recovery. Method of measurement: vital sign monitoring device.;Heart rate. Timepoint: during the surgery and recovery. Method of measurement: vital sign monitoring device.;Arterial blood oxygen saturation. Timepoint: during the surgery and recovery. Method of measurement: vital sign monitoring device.;Patients' satisfaction. Timepoint: In recovery. Method of measurement: 4 point Likert scale. Including low satisfaction, average, good and excellent.