Clinical research on hemodynamic predictors for the progression of major intracranial cerebrovascular stenosis using CFD analysis

Not Applicable

• Conditions: major intracranial artery stenosis

• Registration Number: JPRN-UMIN000042113
• Lead Sponsor: ational Hospital Organization

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-10-14
• Last Update Posted: 17 October 2023
• Study Completion: 2025-03-31

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 650

Inclusion Criteria

Not provided

Exclusion Criteria

1) Cases with stenosis after irradiation 2) Cases with moyamoya disease 3) Cases with stenosis due to dissection 4) Cases with congenital stenosis 5) Cases after bypass surgery on the diseased side (registration is possible if there is an unoperated stenotic lesion on the contralateral side) 6) Patients after angioplasty of the lesion (registration is possible if there are other unoperated stenotic lesions) 7) When the principal investigator and the research coordinator judge that participation in this research is not appropriate

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To identify hemodynamic factors that are significantly involved in the progression of major intracranial artery stenosis using computational fluid dynamics (CFD) analysis.

Secondary Outcome Measures

Name	Time	Method
To identify hemodynamic factors that are significantly involved in the development of symptomatic cerebral infarction due to major intracranial artery stenosis using CFD analysis.