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临床试验/NCT02576873
NCT02576873已完成不适用

Long-term Outcome of End-stage Renal Disease Patients Treated With High-efficiency Hemodiafiltration: a Historical Cohort of a Single-center in South East Asia

Chulalongkorn University1 个研究点 分布在 1 个国家目标入组 66 人开始时间: 2014年3月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
66
试验地点
1
主要终点
Survival rate

研究概览

简要总结

A retrospective cohort study was conducted in 66 end-stage renal disease patients who underwent high-efficiency hemodiafiltration technique in King Chulalongkorn Memorial Hospital between 2001-2013 to determine the survival rate as well as other long-term outcome.

详细描述

Growing evidences suggested the superiority of high-efficiency hemodiafiltration (HDF) which could provide both diffusion and convection in a single therapy compared with the conventional hemodialysis. However, the long-term, upto 10 years, outcome still limited. This retrospective cohort study was conducted in 66 end-stage renal disease patients who underwent high-efficiency hemodiafiltration technique in a single-center, King Chulalongkorn Memorial Hospital, between 2001-2013 to determine the survival rate as well as other long-term outcome

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Aged 18 years or more
  • Be diagnosed end-stage renal disease for more than one year
  • Have been regularly received long-term hemodiafiltration for more than 6 months.

排除标准

  • Patients who received hemodiafiltration less than 6 months

结局指标

主要结局

Survival rate

时间窗: 10 years

The Kaplan-Meier survival curve and mean survival time will be demonstrated for primary outcome.

次要结局

  • Comparison of survival differences between patients who start renal replacement therapy with HDF and who switched from hemodialysis as well as between diabetic and non-diabetic patient.(10 years)
  • Factors that associated with all-cause mortality(10 years)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Khajohn Tiranathanagul

Assistant Professor

Chulalongkorn University

研究点 (1)

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