Effects of Rehabilitation on Muscle Fibre Composition and Capillaries in Chronic Obstructive Pulmonary Disease (COPD) Patients
Not Applicable
Completed
- Conditions
- Chronic Obstructive Pulmonary Disease
- Interventions
- Other: pulmonary rehabilitation
- Registration Number
- NCT01715337
- Lead Sponsor
- Schön Klinik Berchtesgadener Land
- Brief Summary
Pulmonary rehabilitation has been established as an evidence-based and recommended therapy in patients with chronic obstructive pulmonary disease (COPD). The aim of our study is to show a potential change in muscle fibre composition and in the amount of capillaries in quadriceps muscle from pre tob post 3-week rehabilitation. Pulmonary rehabilitation includes standardised exercise training, e.g. cycling and strength training for major muscle groups.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
- chronic obstructive pulmonary disease
- FEV1%pred. < 50%
Exclusion Criteria
- acute exacerbation
- exacerbation in the last 4 weeks
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description pulmonary rehabilitation pulmonary rehabilitation -
- Primary Outcome Measures
Name Time Method Change in the amount of capillaries in muscle fibre type I change from pre (day 1) to post rehabilitation (day 21)
- Secondary Outcome Measures
Name Time Method Change in the cross-sectional area of muscle fibre type IIa Change from pre (day 1) to post rehabilitation (day 21) Change in the cross-sectional area of muscle fibre type I Change from pre (day 1) to post rehabilitation (day 21) Change in the amount of capillaries in muscle fibre type IIa Change from pre (day 1) to post rehabilitation (day 21)
Trial Locations
- Locations (1)
Schön Klinik Berchtesgadener Land
🇩🇪Schönau am Königssee, Germany