NCT00179179
Completed
Phase 2
The Effects of Nutrition Supplementation and Resistance Exercise During Hemodialysis
ConditionsEnd Stage Renal Disease
Overview
- Phase
- Phase 2
- Intervention
- nutritional supplementation
- Conditions
- End Stage Renal Disease
- Sponsor
- Vanderbilt University
- Enrollment
- 11
- Locations
- 1
- Primary Endpoint
- improvement in net protein muscle balance
- Status
- Completed
- Last Updated
- 16 years ago
Overview
Brief Summary
To test the hypothesis that an exercise session combined with adequate nutritional supplementation improves skeletal muscle protein accretion during a hemodialysis session.
Investigators
Eligibility Criteria
Inclusion Criteria
- •On hemodialysis for more than 3 months, on a thrice weekly hemodialysis program.
- •Adequately dialyzed (Kt/V \> 1.2).
- •Age 18-75
Exclusion Criteria
- •Pregnant women.
- •Patients unable to perform exercise
- •Severe unstable underlying disease besides commonly associated with ESRD. Cardiac patients that are stable will be included.
- •Patients hospitalized within the last month prior to the study.
- •Patients with malfunctioning arterial-venous access (recirculation and/or blood flow \< 750 ml/min)
- •Patients receiving steroids and/or other immunosuppressive agents.
Arms & Interventions
1
nutritional supplement plus resistance exercise
Intervention: nutritional supplementation
1
nutritional supplement plus resistance exercise
Intervention: exercise
2
nutritional supplement only (resistance exercise will not be performed)
Intervention: nutritional supplementation
Outcomes
Primary Outcomes
improvement in net protein muscle balance
Time Frame: 10 hours
Secondary Outcomes
- improvement in net whole body protein balance(10 hours)
Study Sites (1)
Loading locations...
Similar Trials
Completed
Not Applicable
Combined Effects of Nutritional and Exercise CountermeasuresMuscular AtrophyMuscle WeaknessNCT00447044University of Arkansas31
Recruiting
Not Applicable
How nutrition supplements may improve exercise capacity in people with Chronic Obstructive Pulmonary Disease attending outpatient pulmonary rehabilitation program.Chronic obstructive pulmonary diseaseRespiratory - Chronic obstructive pulmonary diseaseACTRN12619001354178Chronic Disease Community Rehabilitation Service, Northern Sydney Local Health District80
Completed
Not Applicable
Physical Exercise, Nutrition Supplement and Frailty of Older PopulationSarcopeniaPhysical ExerciseNutrition PoorElderlyNCT04777279Taipei Medical University120
Active, not recruiting
Not Applicable
The effect of exercise and nutritional supplementation on frailty and dialysis-related measures in end-stage kidney disease patientsFrailty and end-stage kidney diseaseUrological and Genital DiseasesISRCTN58806515niversity Hospital Waterford32
Completed
Phase 2
The Effects of Protein Supplementation and Resistance Exercise in Hemodialysis PatientsEnd Stage Renal DiseaseNCT00179140Vanderbilt University26