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Clinical Trials/NCT06132672
NCT06132672
Not yet recruiting
Not Applicable

Identifying and Addressing Historical and Structural Drivers of Medical Mistrust Among Hispanic/Latino Gay, Bisexual and Other Men Who Have Sex With Men

Wake Forest University Health Sciences1 site in 1 country144 target enrollmentJuly 2026

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Human Immunodeficiency Virus
Sponsor
Wake Forest University Health Sciences
Enrollment
144
Locations
1
Primary Endpoint
Change in the amount of use of HIV care services
Status
Not yet recruiting
Last Updated
11 months ago

Overview

Brief Summary

There is an urgent need to address HIV inequities and disparities in the US, particularly within vulnerable communities such as Hispanic/Latino gay, bisexual, and other men who have sex with men (HLMSM).

Detailed Description

Medical mistrust is associated with HIV disparities among HLMSM because mistrust may result in delayed or reduced use of needed HIV prevention (e.g., HIV testing and Pre-exposure prophylaxis (PrEP) uptake) and care (e.g., AntiretroViral Therapy \[ART\]) services. While advances have been made to increase the use of HIV prevention and care services, profound disparities persist, and a need remains for increased understanding of the multilevel drivers of medical mistrust and for effective interventions to address these drivers among HLMSM in the US. This research proposes a mixed-method study that includes rigorous qualitative and quantitative methods to better understand the drivers of medical mistrust among Spanish-speaking, English-speaking, and bilingual (including Spanish and English, or an indigenous language and Spanish and/or English) HLMSM. This study also proposes to refine and test a multilevel intervention designed to address medical mistrust and increase the use of needed HIV prevention and care services among diverse HLMSM in Mecklenburg County, NC, a jurisdiction prioritized by the Ending the HIV Epidemic in the US (EHE) initiative.

Registry
clinicaltrials.gov
Start Date
July 2026
End Date
August 2028
Last Updated
11 months ago
Study Type
Interventional
Study Design
Parallel
Sex
Male

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • reside in Mecklenburg County, NC
  • identify as Hispanic/Latino
  • be ≥18 years of age
  • speak English and Spanish
  • report identifying as male and having had sex with at least 1 man in the past 6 months
  • provide informed consent

Exclusion Criteria

  • less than 18 years of age

Outcomes

Primary Outcomes

Change in the amount of use of HIV care services

Time Frame: baseline to post-intervention up to 18 months

Change in the amount of use of HIV care services - did participant use HIV care in past 12 months

Change in Rate of pre-exposure prophylaxis (PrEP) uptake

Time Frame: baseline to post-intervention up to 18 months

Change in Rate of pre-exposure prophylaxis (PrEP) uptake - did participant use PrEP in past 12 months

Change in Rate of medical mistrust

Time Frame: baseline to post-intervention up to 18 months

The Group-Based Medical Mistrust Scale (GBMMS) - The response key was a Likert-type scale ranging from 1 (strongly disagree) to 5 (strongly agree) and the score range was 12 to 60 - higher scores indicate greater levels of medical mistrust

Change in Rate of Human Immunodeficiency Virus (HIV) testing

Time Frame: baseline to post-intervention up to 18 months

Change in Rate of Human Immunodeficiency Virus (HIV) testing - Self-Report - did participant use testing in past 12 months

Study Sites (1)

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