Medical Mistrust Among Hispanic/Latino Gay, Bisexual and Other Men Who Have Sex With Men (HLMSM)

Not Applicable

Not yet recruiting

• Conditions: Human Immunodeficiency Virus

• Registration Number: NCT06132672
• Lead Sponsor: Wake Forest University Health Sciences

Brief Summary

There is an urgent need to address HIV inequities and disparities in the US, particularly within vulnerable communities such as Hispanic/Latino gay, bisexual, and other men who have sex with men (HLMSM).

Detailed Description

Medical mistrust is associated with HIV disparities among HLMSM because mistrust may result in delayed or reduced use of needed HIV prevention (e.g., HIV testing and Pre-exposure prophylaxis (PrEP) uptake) and care (e.g., AntiretroViral Therapy \[ART\]) services.

While advances have been made to increase the use of HIV prevention and care services, profound disparities persist, and a need remains for increased understanding of the multilevel drivers of medical mistrust and for effective interventions to address these drivers among HLMSM in the US.

This research proposes a mixed-method study that includes rigorous qualitative and quantitative methods to better understand the drivers of medical mistrust among Spanish-speaking, English-speaking, and bilingual (including Spanish and English, or an indigenous language and Spanish and/or English) HLMSM. This study also proposes to refine and test a multilevel intervention designed to address medical mistrust and increase the use of needed HIV prevention and care services among diverse HLMSM in Mecklenburg County, NC, a jurisdiction prioritized by the Ending the HIV Epidemic in the US (EHE) initiative.

Study Timeline

• Study First Submitted: 2023-11-09
• Study First Submitted QC: 2023-11-14
• Study First Posted: 2023-11-15
• Status Verified: 2025-05
• Last Update Submitted: 2025-05-27
• Last Update Posted: 2025-05-28
• Study Start: 2026-07
• Primary Completion: 2028-08
• Study Completion: 2028-08

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: Male
• Target Recruitment: 144

Inclusion Criteria

• reside in Mecklenburg County, NC
• identify as Hispanic/Latino
• be ≥18 years of age
• speak English and Spanish
• report identifying as male and having had sex with at least 1 man in the past 6 months
• provide informed consent

Exclusion Criteria

• less than 18 years of age
• female

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Change in the amount of use of HIV care services	baseline to post-intervention up to 18 months	Change in the amount of use of HIV care services - did participant use HIV care in past 12 months
Change in Rate of pre-exposure prophylaxis (PrEP) uptake	baseline to post-intervention up to 18 months	Change in Rate of pre-exposure prophylaxis (PrEP) uptake - did participant use PrEP in past 12 months
Change in Rate of medical mistrust	baseline to post-intervention up to 18 months	The Group-Based Medical Mistrust Scale (GBMMS) - The response key was a Likert-type scale ranging from 1 (strongly disagree) to 5 (strongly agree) and the score range was 12 to 60 - higher scores indicate greater levels of medical mistrust
Change in Rate of Human Immunodeficiency Virus (HIV) testing	baseline to post-intervention up to 18 months	Change in Rate of Human Immunodeficiency Virus (HIV) testing - Self-Report - did participant use testing in past 12 months

Trial Locations

Locations (1)

Wake Forest University Health Sciences; 🇺🇸 Winston-Salem, North Carolina, United States