ACTRN12605000603617终止不适用
se of a local anaesthetic wound infusion to reduce morphine requirements following major abdominal surgery
Dr Simon Tomlinson, Department of Anaestheisa, Geelong Hospital0 个研究点目标入组 30 人开始时间: 2005年10月5日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- 入组人数
- 30
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 ot stated(—)
- 性别
- All
入选标准
- •American Society of Anesthesiology (ASA) physical status 1, 2 or 3 patients undergoing elective major abdominal surgery via midline laparotomy at Geelong Hospital.
排除标准
- •Pregnant; weight <50kg; allergy to morphine or amide local anaesthetics; ASA physical status 4; severe renal disease ( eGFR < 40ml/min ); significant hepatic impairment; severe respiratory disease (FEV1 < 1.0 l) cognitive impairment or a history of chronic opioid use. Furthermore, patients may be excluded from the trial immediately post-operatively if they meet any of the following criteria: patients who remain intubated post-operatively; post-operative renal or hepatic failure; morphine intolerance or major surgical complications requiring a return to theatre such as sepsis, bleeding or anastomotic breakdown.
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