ACTRN12605000603617
Terminated
Not Applicable
se of a local anaesthetic wound infusion to reduce morphine requirements following major abdominal surgery
Dr Simon Tomlinson, Department of Anaestheisa, Geelong Hospital0 sites30 target enrollmentOctober 5, 2005
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Pain
- Sponsor
- Dr Simon Tomlinson, Department of Anaestheisa, Geelong Hospital
- Enrollment
- 30
- Status
- Terminated
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •American Society of Anesthesiology (ASA) physical status 1, 2 or 3 patients undergoing elective major abdominal surgery via midline laparotomy at Geelong Hospital.
Exclusion Criteria
- •Pregnant; weight \<50kg; allergy to morphine or amide local anaesthetics; ASA physical status 4; severe renal disease ( eGFR \< 40ml/min ); significant hepatic impairment; severe respiratory disease (FEV1 \< 1\.0 l) cognitive impairment or a history of chronic opioid use. Furthermore, patients may be excluded from the trial immediately post\-operatively if they meet any of the following criteria: patients who remain intubated post\-operatively; post\-operative renal or hepatic failure; morphine intolerance or major surgical complications requiring a return to theatre such as sepsis, bleeding or anastomotic breakdown.
Outcomes
Primary Outcomes
Not specified
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