Inspiratory Muscle Training in COVID-19 patients after hospital discharge

Phase 3

Recruiting

• Conditions: Muscle weakness; COVID-19

• Registration Number: RBR-10xczgfz
• Lead Sponsor: niversidade Federal de São Paulo

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2021-04-30
• Study Start: 2021-07-12
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

COVID-19 confirmed; 30 days after hospital discharge

Exclusion Criteria

Smoking; Individuals in clinical deterioration; Signs of respiratory instability or severe dyspnoea at rest; use of supplemental oxygen; limitation in lower limbs; participation in a concomitant pulmonary rehabilitation program.

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To assess the exercise tolerance time, the constant load cardiopulmonary exercise test (CPET) will be used, at 70% of the peak value obtained in incremental CPET, allowing to reach a steady state of the cardiorespiratory and metabolic responses, and to assess exercise tolerance . The percentage of load can be adjusted to induce exercise time within 3-8 min. This test will analyze time limit tolerated, in which it is expected to find a minimum significant difference between groups, with an increase in time tolerated after training of 100 seconds or a difference of 33% compared to the beginning of training. Respiratory and peripheral muscle oxygenation will also be analyzed by the method of near infrared spectroscopy, as well as non-invasive hemodynamic monitoring using transthoracic electrical cardioimpedance.