Vocal-based respiratory training for Long COVID-19 patients with respiratory impairments

Not Applicable

Recruiting

• Conditions: 09.9

• Registration Number: DRKS00028275
• Lead Sponsor: niversitätsmedizin Greifswald/ Unfallkrankenhaus Berlin

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-03-30
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Age >= 18 years
- History of COVID-19 disease (PCR-confirmed) at least 4-6 weeks prior to study inclusion
- COVID-19 associated respiratory dysfunction (shortness of breath, dyspnoea, respiratory rate increase)
- Sufficient knowledge of German as mother tongue or foreign language level at least CI
- Written consent for study participation
- indication for outpatient or inpatient therapy

Exclusion Criteria

- Acute COVID-19 disease
- Patients with marked pulmonary fibrosis or other structural lung changes with functional impact after COVID-19 disease.
- Chronic pulmonary disease prior to COVID-19 (asthma, CORD etc.)
- Pre-existing or COVID-19 neurological disease with impact on respiratory function
- Patients ventilated in the acute situation with abnormal laryngoscopic findings
- Acute laryngitis

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Respiratory parameters (Bodyplethymography) at rest and after exercise using a 6-minute walk test and phonation.

Secondary Outcome Measures

Name	Time	Method
Parameters of cardiological function diagnostics (heart rate and heart rate variability, RR, echocardiography), change in subjective dyspnoea, voice function (Acoustic Voice Quality Index), tone holding time (MPT), Dysphonia Severity Index DSI), mental health, quality of life.