Thirdhand Smoke Contamination in a Neonatal Intensive Care Unit (NICU)

Phase 1

Completed

• Conditions: Nicotine Exposure
• Interventions: Drug: 2% Chlorohexidine Gluconate soap; Drug: 62% ethyl alcohol-based hand sanitizer

• Registration Number: NCT04155697
• Lead Sponsor: The University of Texas Health Science Center, Houston

Brief Summary

The purpose of the study is to quantify the efficacy of hand washing (HW) and ethyl alcohol-based hand sanitizer (S) for third-hand smoke (THS) removal in a sub-sample of non-staff smokers using nicotine wipes on adjacent fingers before and after HW/S.

The hypotheses are that detectable levels of surface nicotine will remain on participants' fingers, regardless of hand washing (HW) and ethyl alcohol-based hand sanitizer (S) attempts and that greater finger levels of surface nicotine will remain after alcohol sanitization compared to hand washing.

Detailed Description

Not available

Study Timeline

• Study Start: 2017-06-07
• Primary Completion: 2018-09-11
• Study Completion: 2018-09-11
• Study First Submitted: 2019-11-05
• Study First Submitted QC: 2019-11-05
• Study First Posted: 2019-11-07
• Status Verified: 2022-05
• Last Update Submitted: 2022-05-03
• Last Update Posted: 2022-05-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 14

Inclusion Criteria

Not provided

Exclusion Criteria

• Unwilling to comply with research procedures (i.e., finger wipes)
• Does not speak English.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Hand washing with soap for thirdhand smoke removal	2% Chlorohexidine Gluconate soap	-
Ethyl alcohol-based sanitizer for thirdhand smoke removal	62% ethyl alcohol-based hand sanitizer	-

Primary Outcome Measures

Name	Time	Method
Nicotine level on finger #2	5 minutes after hand washing or sanitizing	Nicotine will be sampled from one finger of each participant's dominant hand (thumb, index, or middle finger). Finger will be wiped and nicotine level will be quantified.
Nicotine level on finger #1	baseline	Nicotine will be sampled from one finger of each participant's dominant hand (thumb, index, or middle finger). Finger will be wiped and nicotine level will be quantified.
Nicotine level on finger #3	1 hour after hand washing or sanitizing	Nicotine will be sampled from one finger of each participant's dominant hand (thumb, index, or middle finger). Finger will be wiped and nicotine level will be quantified.

Trial Locations

Locations (1)

The University of Texas Health Science Center at Houston; 🇺🇸 Houston, Texas, United States