MRI-based 3D Hip Labrum and Cartilage Morphology in Patients With Hip Deformities Compared to Asymptomatic Volunteers
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Hip Disease
- Sponsor
- Insel Gruppe AG, University Hospital Bern
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- Cartilage Orientation
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
In this study, the investigators seek to describe the normal 3D hip joint morphology in asymptomatic volunteers and compare it to various hip joint deformities. Asymptomatic volunteers will be asked to undergo a non-contrast MRI of the hip at 3 Tesla, utilizing a high-resolution morphologic 3D sequence (3D T2 DESS) that enables the segmentation of labrum and cartilage. 3D morphological parameters of the asymptomatic group will subsequently be compared with the 3D morphological parameters of patients with hip deformities, which were collected as part of a previous retrospective study.
Detailed Description
Hip deformities can cause hip pain and early onset osteoarthritis in young individuals. Correcting these deformities typically involves planning with X-rays and MRI images, which offer a limited view of the hip joint's 3D structure. A comprehensive 3D analysis of hip structures, including cartilage, and labrum, would enhance diagnosis and surgery planning. However, 3D hip morphology hasn't been adequately described for distinguishing deformities. The aim of this study is to describe normal 3D hip joint morphology in healthy participants and compare it to various hip joint deformities (Dysplasia, acetabular protrusion, retroversion, deep hip, and cam deformity). Asymptomatic volunteers will undergo a non-contrast MRI of the hip at 3 Tesla using high-resolution morphologic 3D sequence (3D T2 DESS), which allows segmentation of labrum and cartilage. The 3D morphological parameters of the asymptomatic group will then be compared with those of patients with hip deformities, data sourced from a retrospective study that included 100 patients from the outpatient clinic. These patients underwent direct MR arthrography at 3 Tesla in accordance with the institutional routine protocol at the Department of Diagnostic, Interventional, and Pediatric Radiology at Inselspital.
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- •Individuals who are not considered suitable for MRI (Magnetic Resonance Imaging) for the following reasons:
- •Potential pregnancy
- •Presence of metal fragments in the eye or elsewhere in the body
- •Presence of implants and metallic foreign bodies, such as a pacemaker, heart valve, cerebrospinal fluid shunt, insulin pump, nerve stimulator, or cochlear implant
- •Claustrophobia
Outcomes
Primary Outcomes
Cartilage Orientation
Time Frame: Within 12 Months after MRI
Difference in hip cartilage orientation, measured in inclination (°) and anteversion (°), between healthy volunteers and patients with hip deformities.
Cartilage Thickness
Time Frame: Within 12 Months after MRI
Difference in hip cartilage thickness (mm) between healthy volunteers and patients with hip deformities
Labrum Length
Time Frame: Within 12 Months after MRI
Difference in labrum length (mm) between healthy subjects and patients with hip deformities.
Labrum Area
Time Frame: Within 12 Months after MRI
Difference in hip labrum surface area (both absolute - mm² and relative - %) between healthy volunteers and patients with hip deformities.
Labrum Volume
Time Frame: Within 12 Months after MRI
Difference in hip labrum volume (mm³) between healthy volunteers and patients with hip deformities.
Cartilage Surface Area
Time Frame: Within 12 Months after MRI
Difference in hip cartilage surface area (both absolute - mm² and relative - %) between healthy volunteers and patients with hip deformities.
Cartilage Volume
Time Frame: Within 12 Months after MRI
Difference in hip cartilage volume (mm³) between healthy volunteers and patients with hip deformities.
Secondary Outcomes
- iHOT 12 Questionnaire(ca. 5 minutes before MRI)