Study on Neuroimaging predictors of Outcome in ECT Patients

Completed

• Conditions: Bipolair depression; Depression; Major depressive disorder; 10027946

• Registration Number: NL-OMON43040
• Lead Sponsor: Rijnland Ziekenhuis

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 336

Inclusion Criteria

- Major depressive disorder (MDD) or depressed bipolar disorder, with or without psychotic symptoms
- Clinical indication for ECT
- 18 years or older

Exclusion Criteria

- Schizophrenia, primary alcohol or drug abuse, or any cognitive disorder

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Primary Objectives:<br /><br>Our primary objective is to predict antidepressant response to ECT for<br /><br>individual patients using EEG and fMRI data.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary Objectives:<br /><br>The first secondary objective is to predict cognitive side-effects of ECT for<br /><br>individual patients using EEG and fMRI data. Also, as secondary objective the<br /><br>possible change in EEG and fMRI data directly after a course of ECT and at<br /><br>follow-up will be explored. </p><br>